NIHR CLAHRC for Northwest London

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NIHR CLAHRC for Northwest London

• Collaborations for Leadership in Applied Health
  Research and Care
• November 2008

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Background to CLAHRC bids

• Closing the second translational gap - Cooksey
  Report
• Accelerating research into better care
• CLAHRC bids aimed
• Chronic Disease
• Public Health
• Partnerships between NHS and University
• Broad partnership
• Spans the Comprehensive Local Research Network
  (regional)

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NIHR CLAHRC for NW London

• Improve the delivery of innovative research to
  provide the highest quality of patient care
• Devise and evaluate a systematic approach for the
  rapid adoption of clinically effective
  interventions
• Develop a model for the conduct and application
  of health research that is transferable across
  the NHS
• Develop research capacity and capability across
  northwest London

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The Partnership

• Chelsea and Westminster NHS Foundation Trust
• Imperial College, London
• Acute Trusts in NW London
• Primary Care Trusts in NW London
• Other NHS Organisations
• NHS London
• NHS Institute for Improvement and Innovation
• NHS Direct
• Other HEI
• London School of Hygiene and Tropical Medicine
• Commercial

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Delivering an Integrated System
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Our Focus
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Sharing Experiences
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How is this going to work?
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Funding Sources

• UKCRN Portfolio
• Funding directed towards high quality research
• Competitive at a National Level
• Peer Reviewed
• Competitive Funding
• National Institute for Health Research
• http//www.nihr.ac.uk
• Association of Medical Research Charities
• http//www.amrc.org.uk
• Commercial Funding
• Research Networks
• http//www.ukcrc.org
• http//www.ukcrn.org.uk

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Funding

• CLAHRC funding
• Through host NHS organisation

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What are the opportunities

• Increase research capacity
• Awareness of CLAHRC purpose
• Supporting NHS staff
• Research
• Establishing an evidence base
• Undertaking research
• Use of information
• Knowledge management/transfer
• E learning
• Maximising across the CLAHRC(s)

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Patient and Public involvement

• Access
• Dissemination
• Supporting PPI in general

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QA
www.clahrc-northwestlondon.nihr.ac.uk
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www.rdfunding.org.uk
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Funding Applications

• Read the guidelines
• Make sure your proposal is within the scope of
  the bid and meets all criteria
• Seek financial advice early!
• Familiarise yourself with local requirements
• Check application guidelines
• Research Costs (research funder e.g. NIHR, MRC)
• NHS Support Costs (DH/NIHR via research networks)
• Treatment Costs (Commissioning)

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How to improve applications

• Service user involvement
• Development of the grant application
• Design and management of the research
• Undertaking research
• Analysis
• Dissemination of findings
• Clear dissemination policy
• Field a strong team
• Invite critical review before you submit

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Ethics and Governancehttp//www.nres.npsa.nhs.u
k/

• What requires ethical approval?
• Includes tissue and data collection
• New IRAS application process (www.myresearchprojec
  t.org.uk)
• Seek advice from your local research office
• Ethical approval (Site Specific Assessment)
• Trust RD approval
• Other approvals
• EudraCT registering RCTs
• MHRA (investigational medicinal products and
  medical devices)
• PIAG
• Research Governance Framework
• Good Clinical Practice Training
• Monitoring and Auditing

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Example Project Flow
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Patient and Public Involvement Cascade
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Shifting the Balance
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Making Step Change Happen
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Opportunities I

• Research Project (site or organisation)
• Key research staff or delivery staff funded
• Training and support from expert team
• Peer reviewed publications
• CLAHRC Partner
• Full access to training programme
• Staff development
• Dissemination supported implementation
• Support programme

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Opportunities II

• Round 1 April 2008
• Medicine management
• COPD and Pneumonia
• HIV
• Round 2 and 3
• Open competition bids from NW London partnerships
• Technology, therapeutics, service delivery
• Roll-Out of projects from Round 1
• Links with other research programmes
• Patient and public focus
• Action Research and Improvement Methodology