ADOPT: Treatment effect on primary outcome

1
ADOPT Treatment effect on primary outcome
N 4351
40
Hazard ratio (95 CI) Rosiglitazone vs
metformin, 0.68 (0.550.85) P lt 0.001
Rosiglitazone vs glyburide, 0.37 (0.300.45) P lt
0.001
Glyburide
30
Cumulative incidence of mono-therapy failure()
Metformin
20
Rosiglitazone
10
0
0
1
2
3
4
5
Years
Kahn SE et al. N Engl J Med. 20063552427-43.
2
ADOPT Adverse events
Investigator reported Self reported
Kahn SE et al. N Engl J Med. 20063552427-43.