Viruses, Viroids, and Prions

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Chapter 13

• Viruses, Viroids, and Prions

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Viruses

• Obligate intracellular parasites
• Host range
• Viral size

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Viral Structure

• Virion
• Nucleic acid
• DNA
• RNA
• Capsid
• Capsomeres
• Envelope
• Spikes

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Morphology

• Helical

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Morphology

• Helical
• Polyhedral

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Morphology

• Helical
• Polyhedral
• Enveloped

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MOrphology

• Helical
• Polyhedral
• Enveloped
• Complex

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Taxonomy

• Named according to where it was discovered and
  what it did
• Newer viruses
• Type of nucleic acid
• Method of replication
• Shape and size

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Growing viruses in the lab

• Bacteriophages

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Growing viruses in the lab

• Bacteriophages
• Animal viruses
• In animals
• Embryonated eggs

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Growing viurses in the lab

• Bacteriophages
• Animal viruses
• In animals
• Embryonated eggs
• Tissue cultures

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Growing viruses in the lab

• Bacteriophages
• Animal viruses
• In animals
• Embryonated eggs
• Tissue cultures
• Primary cell line
• Diploid cell line
• Continuous cell line

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Viral multiplication

• Bacteriophages
• Burst time
• Burst size
• Lytic cycle
• Attachment
• Penetration
• Biosynthesis
• Maturation
• Release

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Viral multiplication

• Bacteriophages
• Lytic cycle
• Lysogenic cycle

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Viral multiplication

• Bacteriophages
• Animal viruses
• DNA viruses

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Viral multiplication

• Bacteriophages
• Animal viruses
• DNA viruses
• RNA viruses

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Other concerns

• Viruses and cancer
• Latent viral infections

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Other concerns

• Viruses and cancer
• Latent viral infections
• Persistent viral infections
• Prions

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Other concerns

• Viruses and cancer
• Latent viral infections
• Persistent viral infections
• Prions
• Plant viruses and viroids