Title: UC BioSTAR
1UC BioSTAR
- Founded in 1996, the BioSTAR Project is a UC
Systemwide industry-university matching grant
program that jointly supports new biotechnology
research opportunities throughout the nine
campuses and three National Laboratories of the
University of California System. - One of six sector programs of the
Industry-University Cooperative Research Program
(IUCRP), BioSTAR is dedicated to strengthening
Californias economy.
2THE UC DISCOVERY GRANT Gateway to
Industry-University Partnerships
3BioSTAR Mission Goals
- Enhance Californias economic competitiveness.
- Stimulate growth and investment in California
businesses and jobs. - Improve health care, food production,
manufacturing, and the environment. - Accelerate delivery of public benefits from UC
research and education.
4BioSTAR Funding
- Private industry sponsors match BioSTAR grant
funds at least 11. - To date, 110 California companies have
participated in BioSTAR grants 88 of these
sponsors were small businesses. - Calls for proposals take place in the Spring,
Fall, and Winter.
5Typical Grant Size/Duration
- Grants run 1-4 years
- 25K-1.5M
- Up to 20 in-kind allowed
- No upper limit
6Funding Process
7Funding Priorities
- Funding new, innovative research
- Must be jointly supported by a Private Sponsor or
a group of private sponsors. - Research areas related to biotechnology include
basic sciences and biochemical engineering, and
the nature of the research is pre-commercial,
ranging from basic to proof-of-concept research. - Proposals for clinical trials or for medical
engineering (e.g., prosthetics, etc.) generally
are not appropriate.
8BioSTAR Research Fields
- BioSTAR aims to improve and expand California's
economy through collaborative research
partnerships across a broad spectrum of
biotech-related interests including
- Agriculture
- Biomaterials
- Bioinformatics
- Drug Discovery
- Environmental Sciences
- Marine Sciences
- Structural Biology
- Technology Development
- Veterinary medicine
9Selected BioSTAR-Funded Projects
- Characterization of protease inhibitors as
potential treatment for neurodegenerative
diseases - Targets of hypoxic response in epithelial tumors.
- Nanowire-Based Sensors
- Synchronized Approach for Large Number of
Pathogen Detection Using Microarray Technology - Tissue-engineering techniques for the treatment
of stress urinary incontinence - Virus-Cell Fusion Inhibitors
- Investigation of deep marine sediment microbes
for the development of crop protection products.
10Life Sciences Information Technology(LSIT)
- Launched in 1999, LSIT builds partnerships at
the interface of life sciences and mathematics,
statistics, computational and information
sciences and engineering. - Must develop new informatics methods, or new
applications. - Use of existing technology in routine application
is not enough.
11Selected LSIT-Funded Projects
- Advanced Computerized Patient Records
- New Computational Methods for High-performance
Automated Genomic Analysis - Genome-wide SNP Discovery
- Computational Analysis of Alternative Splicing
and Termination - Linking Genotype to Phenotype to Optimize Cancer
Treatments - High-Throughput Screening Against Virtual
Receptors
12 Private Sponsor Qualifications
A Private Sponsor may be any company or
for-profit business entity that satisfies one of
the following criteria
- California-based
- Maintains R D or manufacturing facilities in
California that are related to the proposed
research - Based outside of California but has a research
and development alliance with a
California company that is related to the
proposed research - Based outside of California but provides strong
justification that the research sponsored will
demonstrably benefit California economy.
13Proposal Review Criteria
- Quality and originality of the proposed research
and achievable milestones. - Qualifications of the personnel, adequacy of the
facilities and other resources. - Relevance of the project to the goals and
concerns of BioSTAR. - Significant benefits for California, e.g.,
- development of new knowledge/skilled workforce,
attract greater investments, create new
California jobs, solve California problems, or
otherwise benefit the State as defined and
justified by the applicants - Budgetary justification.
- Binding Letter of Intent to Fund from the Private
Sponsor.
14Factors Given Additional Consideration
- PI is a junior faculty investigator.
- Research plan addresses a critical scientific
problem that is limiting biotechnology industry
development or manufacturing in California. - Private Sponsor commits to doing subsequent RD
and manufacturing in California. - Private Sponsor has fewer than 50 employees.
- Further leveraging of BioSTAR and Private Sponsor
contributions to the project, e.g. through SBIR
grants, contributions from a third party
co-sponsor. - Private Sponsor's financial contribution exceeds
the minimum requirement.
15Intellectual Property
- BioSTAR generally supports research projects
performed by University scientists using
University facilities. - All rights to inventions or discoveries arising
from research conducted under this Research
Agreement shall belong to the University. - University shall offer Private Sponsor(s), a
time-limited right to negotiate an exclusive
commercial, royalty-bearing license, to make,
use, and sell any patentable inventions conceived
and first actually reduced to practice in the
performance of research under this Research
Agreement.
16Private Sponsor Benefits
- Leverage scientific/technical expertise
- Expand effort around strategic RD direction
- Advance scientific knowledge in field directly
relevant to strategic direction - Leverage RD funding
- Pilot novel research direction
17UC Researcher Benefits
- Access to company know-how
- Access to expensive equipment/reagents
- Access to economic information
- Student/Post-doc experience with companies
- future jobs
- Fast-track patent applications
18Industry Partners Include
- Abbott Laboratories Isis Pharmaceuticals
- Amgen Maxygen
- Aventis MitoKor
- Berlex ONYX Pharmaceuticals
- Canji Pangene
- Chiron Rigel
- FibroGen Roche Bioscience
- Geron Titan Pharmaceuticals
- IDEC Pharmaceuticals Tularik
19BioSTAR Spring 2002 Proposal Submission
Deadlines
- Notice of Intent Submission April 23, 2002
- Proposal Submission May 2, 2002
- Notification of Review Outcome June 13, 2002
- Research Agreements August 12, 2002
- Grants Commerce August 13, 2002
- http//uc-biostar.berkeley.edu
20LSIT Spring 2002 Proposal Submission Deadlines
- Notice of Intent Submission May 14, 2002
- Proposal Submission May 23, 2002
- Notification of Review Outcome June 28, 2002
- Research Agreements September 2, 2002
- Grants Commence September 3, 2002
- http//uc-lsit.berkeley.edu
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