Title: Sources of Funding for Academic Surgeon
1- Sources of Funding for Academic Surgeon
- Career Development
James L. Mohler, M.D. Chair and Professor Gary
Smith, Ph.D. Distinguished Professor Department
of Urologic Oncology Prostate Cancer Research
Program Roswell Park Cancer Institute, Buffalo, NY
Leo Giambarresi, Ph.D. Program Manager Prostate
Cancer Research Program, CDMRP
2POTENTIAL SOURCES OFFUNDING
- National Institutes of Health (NIH)
- Department of Defense (CDMRP)
- Other PHS divisions CDC, AHRQ, NSF
- VA
- Foundations
- Pharmaceutical companies
3NIH OFFERS SOMETHING FOR EVERY CAREER LEVEL
4Types of NIH Grant Awards
- NIH Grants Office of Extramural Research
- http//grants1.nih.gov/grants/oer.htm
- Grant Mechanisms
- National Research Service Awards (F_ T_)
- Pre-and post-doctoral fellowships
- Career Development Awards (K_)
- Research Grant Programs (R_)
- Small Business Development
- SBIR (R41) Small Business Innovation Res
- STTR (R43) Small Business Tech Transfer
5National Research Service Awards (NRSA)
- Established by the NRSA Act of 1974
- Individual Fellowships (F31, F32, F33)
- Institutional Training Grants (T32, T35)
- Only NIH award that goes to an individual
- 5 years support for grad/med students
- 3 years support for post-doctoral fellows
- Must be a U.S. citizen or permanent resident
- Pay back provisions
6NRSA Grant Application
- Scholastic Performance
- Research Experience / Training Plan
- Personal Data Form
- Biographical Sketch
- Facilities and Commitment
- Criteria for evaluation
- candidate
- training plan
- success of training program
7Individual NRSA Grants
- F31 Ruth L. Kirschstein National Research
Service Award Predoctoral Fellowship - support for research training leading to a Ph.D.
(or the equivalent research degree) or a combined
M.D./Ph.D. (or other combined professional
research doctoral degrees) in the biomedical or
behavioral sciences - F32 Ruth L. Kirschstein National Research
Service Award Postdoctoral Fellowship - support for postdoctoral research training to
individuals to broaden their scientific
background and extend their potential for
research in specified health related areas
8Institutional NRSA Grants
- T32 NRSA Institutional Training Grants
- support training opportunities at the predoctoral
or postdoctoral level at qualified institutions - Program Director is responsible for selecting the
trainees and administering the program - T36 - Minority Access to Research Careers (MARC)
- support to increase the number of well-trained
minority scientists in biomedical disciplines and
strengthen the research and teaching capabilities
of minority institutions
9NIH Career Development Programs
- Purposes include to provide
- mentored development of research careers
- transitions of career emphasis
- protected time for research by clinicians
- support for outstanding scientists with a
sustained level of high productivity - 13 different mechanisms
- Match with the stage of career
- Mentored, Mid-career, Senior
- Can be interactive with other NIH Awards
- Different availabilities/eligibilities at each
institute
10Mentored Research Grants
- K01 Mentored Research Scientist Development
Award - provide research scientists with a sponsored
research experience that will help the applicant
gain expertise in a new research area or
demonstrably enhance the applicants scientific
career - Replaced July 2, 2006 by the NIH Pathway to
Independence - K22 Career Transition Award
- support newly trained investigators (basic or
clinical) to develop their independent research
skills through a two phase program. - initial period involves an intramural appointment
at the NIH - final period of support is conducted at an
extramural institution. - research in Cancer Prevention Control
11NIH Pathway to Independence Award K99/R00
- Postdoctoral scientists receive both mentored
independent research support from the same award - 1-2 year mentored phase (K99)
- independent phase, occurs in years 3-5 (R00)
- Goal to facilitate awardee
- secure an assistant professorship (or equivalent)
- establish an independent research program
- apply for an investigator-initiated grant
12Consider the review criteria
- The candidate your background and potential to
develop into an independent researcher - Research plan its scientific merit,
significance, feasibility relationship to your
career plans - Training/career development plan its components
how well it fits the research plan - The sponsor his/her track record as both a
researcher and mentor - Institutional environment commitment to the
training/career development of the candidate
13Identifying a Sponsor/Mentor
- With a track record of successful training and
research - With a commitment to you your career goals
- He/she need not be your research advisor
- More than one is OK!
- Should have
14Institutional Commitment
- To your time
- To your professional development
- To your research efforts
- Protected time
- Protected time
- Protected time
- Protected time
15Mentored Clinical Grants
- K08 Mentored Clinical Scientist Development
Award - Support the development of outstanding clinical
research scientists - Provide specialized study for clinically trained
professionals who are committed to a career in
research and have the potential to develop into
independent research scientists - K12 Mentored Clinical Scientist Development
Program Award - Support newly trained clinicians appointed by an
institution for development of independent
research skills and experience in a fundamental
science within the framework of an
interdisciplinary research and development
program. - K23 Mentored Patient-Oriented Research Career
Development Award - support for the career development of
investigators who focus their research endeavors
on patient-oriented research - provides support for a period of supervised study
and research for clinically trained professionals
16Other Award Mechanisms
- R15 Academic Research Enhancement Award (AREA)
- support small-scale research projects conducted
by faculty in domestic institutions that
primarily award baccalaureate degrees - S06 Minority Biomedical Research Support (MBRS)
- provide funds to strengthen the biomedical
research and research training capability of
ethnic minority institutions, thus creating a
more favorable environment for increasing the
involvement of minority faculty and students in
biomedical research - K07 Academic Career Award
- support
- junior candidates who are interested in
developing academic and research expertise in a
specific area - senior individuals with acknowledged scientific
expertise and leadership skills who are
interested in improving the curricula and
enhancing research capability within an academic
institution
17Career DevelopmentTransition from Post-Doc to
Faculty
- K99/R00 Pathway to Independence
- K08 M.D. proposing basic research in a
laboratory environment - K12 M.D. proposing basic research in an
interdisciplinary environment - K23 M.D. proposing clinical research
- K24 Mid-career mentor for physician scientists
18More Funding Information
- You can sign on to list serves
- NIH Funding http//nih.gov/grants/oer.htm
- DOD Funding http//cdmrp.army.mil/
19Award Mechanisms From Traineeships to
Established Independent Investigator Awards
Training
Early Career Established
Pre- Doctoral
New Investigator
Postdoctoral PhD
Idea Development
Postdoctoral MD
CAREER DEVELOPMENT
Physician Research
Synergistic Idea Development
Clinical Trial
Laboratory-Clinical Transition Stage I
20Example Prostate Cancer Training Award
- Intent Provide prostate cancer research training
opportunities to individuals in the early stages
of their careers - Key Features
- Supports Ph.D. or M.D. predoctoral and
postdoctoral trainees - Emphasis on Trainee, Mentor and Training Program
- Peer Review Criteria Written for both Ph.D. and
M.D. applicants - Funding Summary
21Physician Research Training Award
- Intent Recruit and prepare physicians for
careers in research through a mentored training
experience - Key award features
- Requires 3-5 y commitment
- Mentor must have an established research program
in cancer research - Minimum 50 effort
- 130K direct costs per year for 3-5 years
- Eligibility
- Physicians in the last year of graduate medical
education or fellowship, or within 3 years of
appointment as an Assistant Professor or
equivalent
22New Investigator Awards
- Intent To support innovative ideas and new
technologies from investigators in the early
stages of their careers - Key Award Features
- Innovation critical
- Preliminary data not required
- Must enlist collaborator(s) with relevant
experience - Eligibility
- Independent investigator with access to research
facilities - Must be within 6 years of fellowship or
postdoctoral position - Must not have received non-mentored extramural
research funding 100K (direct) in aggregate - Funding 225K direct costs for 3 years
23Idea Development Awards
- Intent To encourage innovative approaches to
prostate cancer research from established
investigators in prostate cancer and those from
other fields who want to move into prostate
cancer - Key Award Features
- Innovation critical
- Preliminary data relevant to prostate cancer
required - Eligibility
- Independent investigator with access to research
facilities - Must be Assistant Professor (or equivalent)
- Funding 375K direct over 3 years
24Clinical Trial Awards
- Intent Support rapid initiation and efficient
execution of novel Phase I, II or I/II clinical
trials - Key award features
- Focus should be on new interventions
- Preclinical efficacy must be established already
- A study coordinator is required
- IND or IDE application must be submitted before
the proposal receipt date - Eligibility
- Independent investigator with access to research
facilities - Must be at or above the level of Assistant
Professor (or equivalent) - Funding 750K direct costs over 3 years
25DoD-Supported Career Development Sequence
- Physician Research Award or Postdoc Award
- New Investigator Award
- Idea Development Award or Clinical Trial Award