RCOX RNH2 COX

1
??????? ?????, ??????? ??????
R-COX ? R-NH2 COX (??????)
?????
Cl2 OH ? R-NH2
???????
H2O, ?
NaN3 ?
R-NH2
?????
1. H2SO4, CHCl3
NaN3
R-NH2
2. NaOH
2
????????? ?????? ????? ??????? ?? ?? ?????? ???
???? ???? ?????? - ?????
?????
-H2O
Cl2
OH
-Cl
OH, -H2O
-Cl
H2O
R-NCO
..
..
????-?????
- CO2
RNH2
3
???????? ????? ???? ???? ???? ?????? ????? ??????
?? ????? ?????
-N2
..
..
?????? ??????? ?? ???? ???? ????? ??????
????????? (??????? ???? ?????? ??????)
H2SO4
HN3
-H2O
4
??????
XBr, Cl, OCOR, OR
?? ?????? ?? ?????
2 RNH2
RNH2
HX
RNH3 X
?? ????? ??????. ????? ?????? ?????? ?????. ????
?????? ???? N-???????
HNO2
NaNO2
HCl
5
??????
- H2O



NO
N?O
HO-NO H
H2O-NO
..
R2N-H
- H
R2N-NO
??????? ???????? ????????? ??? ????, ???? ????
?????? ?? ???? ??????. ???, ????? ???? ?????
??????????? ???????.
NaNO2
HCl
6
????? ?????? ????? ?? ?????? ???????? ??? ???????
?????????.
H
-H
H
-H2O
R-NN-OH

R-N ? N
????? ????????? ???? ??????, ?????? ???? ???????
????? ?? ???? ????????
NaNO2, HCl
13
H2O
25
CH3CH2CHCH2
5
3
26
7
3
7
?????? ???? ??? ????????? ???? ???? ???? ?????????
NaNO2
HCl