Description of Ibogaine Treatments made in Brazil

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Description of Ibogaine Treatments made
in Brazil
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Dr. Bruno Rasmussen Chaves M.D. Dr. Cleuza
Canan Psychologist

• Ibogaine Treatment Facility
• M.P.P. Gonçalves Hospital
• Santa Cruz do Rio Pardo,
• São Paulo, Brazil

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In Brazil we have been doing treatments with
Ibogaine since 1997, in order to treat drug
addiction, with excellent results.
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• Brazil has a huge public health problem with
  crack/cocaine users, which reaches the number of
  2-4 of the population, (190 million), and a
  small (until nowadays) problem with heroin
  ( 50 cases)
• PROAD (Drug Addicts Orientation and Care Program,
  Federal University of São Paulo, 2006)

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• We have treated until February 2009
• -54 patients (51 males, 3 females)
• -from 22 to 49 years old
• -53 of these from crack/cocaine addiction
• -one from opiates addiction.

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• Here we will discuss the clinical procedures
  related to the treatment itself, it's safety, and
  not the aftercare outcome, although we could not
  talk about Ibogaine and not say that it is very
  effective in attenuating the dependence and in
  stabilizing the life of the majority of the
  persons who takes it.

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• All patients seeking to be treated are
  evaluated by the psychologist, then by the
  clinician, and asked to perform some basic blood
  tests (hemogram, liver enzymes, creatinine,
  sodium, potassium, magnesium, and sugar blood
  test) and an EKG.

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Exclusion Criteria

• Patients presenting with any of the following
  conditions are excluded
• -pregnancy
• -significant clinical issues, like non
  controlled arterial hypertension, non-controlled
  diabetes, previous myocardial infarction, cardiac
  arrhythmias, renal failure, hepatic failure,
  Alzheimer and Parkinson diseases.

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Exclusion Criteria

• Psychiatric diseases
• -Schizofrenia
• -Anti-social personality
• Social issues
• -Living alone subject
• -subject who has not a proper social and
  professional environment to come back to

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• After this evaluation, the treatment is
  scheduled, and is asked for the patient that
  he/she stays abstinent from crack/cocaine for at
  least 20 days. The patient may be hospitalized if
  he/she feels that he/she could not achieve this
  goal alone, at home.

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• In the day before the treatment the patient is
  asked to eat light food in the evening, and to
  drink a lot of water until midnight. After that,
  he is asked not to eat or drink anymore.

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M.P.P.Gonçalves Hospital
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• In the day of the procedure the patient
  arrives at the hospital at 7 oclock, he/she
  takes 20 mg of domperidone, and after 30 minutes
  he takes 12-20 mg/kg of Ibogaine HCL. Although
  domperidone is described as a drug that has a
  possible risk of inducing a Torsades de Points
  arrhythmia, we have never seen it. All the time
  the subject is monitorized, which includes
  cardiac monitorization, blood pressure measures,
  and oxymetric monytorization.

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• The average patient throws up a few times,
  some few a little more, he shows ataxia, tremors
  and visualizations, but there was no significant
  clinical occurrences during this number of
  procedures, except for

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• -one patient (male, 25 ) that had a drop in the
  cardiac frequency to 45 bpm, with the EKG showing
  sinusal bradycardia, which lasted for 3 minutes,
  without hemodinamic repercussions or symptoms.

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• -Another patient (male, 30) that had thrown up
  several times, and presented with an upper
  gastrointestinal bleeding, probably a
  Mallory-Weiss syndrome, (where the repeated
  vomiting causes a rupture of the mucosae of the
  terminal esophagus and bleeding). This patient
  had not any hemodinamic repercussions, performed
  an upper gastrointestinal endoscopy which
  confirmed the Mallory Weiss syndrome and was
  discharged 2 days later in a very good condition.

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• Its interesting to say that one patient,
  (male, 38), had a history of being shot by a
  firegun, years before the treatment, and had 2
  bullets still on his body, one near the heart,
  and another located at the T 10 vertebrae, he was
  performed a parcial pancreatectomy, a left
  pneumectomy, a left nefrectomy and a splenectomy.
  Although all this procedures, he was in a good
  health situation, and was treated, with
  absolutely no intercurrences.

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• In all of this 54 cases treated, absolutely no
  complications were seen, what makes us conclude
  that the treatment with Ibogaine seems to be a
  safe procedure.

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Conclusion

• It is very important to follow a rigorous
  clinical protocol and to be aware of
  pre-treatment clinical conditions, mainly cardiac
  problems.
• It is important to the patient to be rested,
  well hydrated, in good clinical conditions.

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Sedation

• We strongly recommend not to sedate the
  patient, shortly after the treatment, in order to
  the subject fully feel ibogaine effects. But when
  it is necessary, we use diazepam.

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Howard Lotsof
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Thank you