Genital tract IgA may help explain HIV1 resistance

1

• Genital tract IgA may help explain HIV-1
  resistance
• Difficult to purify from genital tract secretions
• Cloning produces unlimited IgA for in-depth
  characterization
• Variable genes isolated from cervical B-cells
• Selected genes pre-screened against gp120IIIB
• MAbs produced by cultured animal cell transfection

2
Characterization neutralization, epitope
mapping, transcytosis
(Positive Control)