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1. Mendelian genetics. 2. Molecular genetics ... What is required is a molecular description of Mendelian processes and properties ... – PowerPoint PPT presentation

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Title: various


1
various
  • 1. organise extra seminar

2
The Special Sciences
  • Their domain is limited economics psychology
    biology
  • These disciplines seem to involve laws
  • exceptions are not explicable in terms of the
    special science in question
  • Sellers and buyers may be crazy
  • Crazy is not an economic category

3
Arguments for the autonomy of the special sciences
  • (i) economics not reducible to physical science
  • Each economic events has a physical description
  • But all price rises, say, have nothing physical
    in common
  • And units of money have nothing physical in
    common
  • Economic generalisations cannot therefore be
    captured by laws couched in physical terms

4
  • Economics, though, still involves laws Laws of
    Economics (and not physics)
  • Cf. positivist conception of science all
    respectable sciences must reduce to physics

5
(ii) Putnams round and square pegs
  • Why does a round peg fit into a round hole and
    not a square one
  • 2 explanations
  • (i) because it is the same shape and size
  • (ii) a complex explanation involving the
    positions of all the subatomic particles that
    make up the peg and the hole

6
  • (i) applies across a wide range of cases it is a
    more general explanation
  • (i) could therefore be used to predict what would
    happen in relevantly similar cases
  • It is counterfactual supporting thus a law
  • But round pegs have nothing physical in common
  • They have something geometric in common

7
  • I am suggesting, roughly, that there are special
    sciences not because of the nature of our
    epistemic relation to the world, but because of
    the way the world is put together not all
    natural kinds (not all classes of things and
    events about which there are important,
    counterfactual supporting generalisations to make
    (are, or correspond to, physical natural kinds.
    (Fodor, Special Sciences, 113)

8
The unification of Science
  • science is unified in that all sciences will
    reduce to physics
  • Weaker conception of unification
  • The laws of the special sciences cannot be
    reduced to those of physics
  • But all economic events, say, can be given a
    physical description

9
  • It seems to methat the classical construal of
    the unity of science has really misconstrued the
    goal of scientific reduction. The point of
    reduction is not primarily to find some natural
    kind predicate of physics co-extensive with each
    natural kind predicate of a reduced science. It
    is, rather, to explicate the physical mechanisms
    whereby events conform to the laws of the special
    sciences. (Fodor, Special Sciences, 107)

10
  • If science is to be unified, then all such
    taxonomies those of the special sciences must
    apply to the same things. If physics is to be the
    basic science, then each of these things had
    better be a physical thing. But it is not further
    required that the taxonomies which the special
    sciences employ must themselves reduce to the
    taxonomy of physics. It is not required, and it
    is probably not true. (Fodor, Special
    Sciences, 114)

11
Can biology be reduced to physics?
  • biology is a varied discipline
  • We shall focus on genetics
  • The inheritance of traits
  • Two kinds of genetics
  • 1. Mendelian genetics
  • 2. Molecular genetics

12
  • Reduction of genetics to physics would be via
    various steps
  • Mendelian genetics ? molecular genetics ?
    biochemistry ? chemistry ? physics

13
Mendelian Genetics
  • Gregor Mendel and sweet peas
  • Phenotype the outward appearance of offspring
  • Crossing a red and a blue sweet pea produces
    offspring with various phenotypes red, blue
    white sweet peas
  • Why?
  • Theoretical explanation
  • (Theoretical not a pejorative term)
  • Theories explain the observed phenomena in terms
    of the unobserved

14
The Gene
  • These explain phenotypic differences
  • Genes come in pairs, one from each parent

15
Eye colour
  • Gene B codes for brown eyes
  • Gene b codes for blue eyes
  • If you are BB then you have brown eyes
  • If you are bb then you have blue eyes
  • homozygous
  • But what if you are Bb?
  • Heterozygous
  • One gene dominates the other
  • B is dominant
  • b is recessive
  • If you are Bb then you have brown eyes

16
Laws of genetics
  • BB BB parents
  • B B sex cells
  • BB offspring
  • all brown

17
  • BB bb parents
  • B b sex cells
  • Bb offspring
  • all brown

18
  • Bb Bb parents
  • B b B b sex cells
  • BB Bb bB bb offspring
  • ¾ brown ¼ blue

19
complexities
  • Traits coded for by multiple genes
  • Pleiotropy same gene affecting lots of traits
  • mutations

20
Reduction to molecular genetics
  • What will need to be explained in molecular
    terms?
  • What is required is a molecular description of
    Mendelian processes and properties
  • 1. e.g. genes, dominance, heterozygous
  • 2. The laws of genetics
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