BRIN http:www.med.und.nodak.edubrin

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BRIN http//www.med.und.nodak.edu/brin

• Biomedical Research Infrastructure Network
• NIH grants to 24 states
• Multi-institutional infrastructure award 3 yrs,
  6M
• Administrative Core
• Bioinformatics Core
• Start-up Core
• Tribal College/Baccalaureate Science Core

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Bioinformatics Core

• 250 K /three years for purchase of biomedical
  electronic resources
• Journals
• Databases
• Bioinformatics software

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BRIN has made available

• Vector NTI analysis software
• 41 research journals
• Nature journals
• Cell Press journals
• Annual Reviews Biomedical Suite
• BioMed Central
• Selected additional resources at UND NDSU

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Open the door

• BRIN Resources
• Free Resources

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Finding the BRIN Resources

• BRIN web site
• http//www.med. und.nodak.edu/ brin
• On left hand side under FYI click on Online
  Electronic Resources

• Your library web sites
• Journal lists
• Links to the BRIN page

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Whats next? You have a problem find out the
mechanism of action, structure and toxicity of
Leptin

• Use an indexing service to find the journals that
  will have information?

• Try to find information directly from a journal?

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Directly to a journal?

• Which one?
• Searching mechanisms?

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Directly to the journals?

• Only when they are electronic
• Select the journal according to information
  needed
• For example, need background, go to Annual
  Reviews
• Search across all the Annual Reviews

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Use an indexing service?

• Which one?
• PubMed
• Free
• Over 14 million citations for biomedical journal
  articles going back to the 1950s
• http//pubmed.gov

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Searching mechanism?

• Get definitions by using MeSH (Medical Subject
  Headings)
• Leptin A 16-kD peptide hormone secreted from
  white adipocytes and implicated in the regulation
  of food intake and energy balance. Leptin
  provides the key afferent signal from fat cells
  in the feedback system that controls body fat
  stores.Year introduced 2000
• Search the database and add limits, such as
  Review articles, English only, Humans, etc.

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Some tricks

• Limits
• Single Citation Matcher
• Sort by Journal

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Other free resources

• PubMed Central Journals
• 86 journals with full text
• Some current issue, some start after six months
  old
• Highwire Press Journals
• MedlinePlus
• MedlinePlus.gov
• ToxNet and ToxTown
• http//toxtown.nlm.nih.gov/

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Important URLs

• ND BRIN http//www.med.und.nodak.edu/brin/
• PubMed http//pubmed.gov
• PubMed Central http//www.pubmedcentral.nih.gov/
  
• Highwire Press http//highwire.stanford.edu/list
  s/freeart.dtl
• MedlinePlus http//medlineplus.gov
• ToxNet http//toxnet.nlm.nih.gov/
• ToxTown http//toxtown.nlm.nih.gov/

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Need more help?

• PubMed tutorial at
• http//www.nlm.nih.gov/bsd/pubmed_tutorial/m1001.h
  tml
• Check with your librarian
• E-mail me at jrieke_at_medicine.nodak.edu
• Try our web site link to Live Help at
• http//harley.med.und.nodak.edu/

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Step-by-Step Searching a Journal Site

• Annual Reviews at
• http//arjournals.annualreviews.org/
• Select Search button
• Put in search term Leptin
• Under publications, select Biomedical Sciences
• Hit the search button
• 99 matches found

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Searching PubMed

• Go to http//pubmed.gov
• On the left hand side, click on MeSH database if
  you are not sure what your term should be
• Then go back to PubMed and enter the term
• Use limits to keep down the numbers of articles
  and to make it more focused
• Combine with AND if you want to include other
  facets of the search

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