The Idaho BRIN Program

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The Idaho BRIN Program

• Building Opportunities for Biomedical Research

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An Opportunity

• National Institutes of Health (NIH)
• BRIN Program
• (Biomedical Research Infrastructure Network)

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Growing Biomedical Research in Idaho

• How Do We Get There from Here?

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BRIN Program in Idaho

• Overview of the BRIN Program
• Bioinformatics
• Research Facilities Enhancement
• Student Opportunities
• Faculty Development
• Outreach Activities
• Collaborative Efforts

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Getting Three Universities to Work Together !

• UI, ISU, BSU
• Put Science before Politics

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Reasons for Low NIH Biomedical Research Funding

• Heavy teaching loads
• Inadequate infrastructure
• Low graduate student stipends
• Few undergraduate student researchers
• Disadvantaged students rarely participate

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BRINBiomedical Research Infrastructure Network

• Awarded October 2001
• 8 million over three years
• Build a network and collaboration
• University of Idaho, Dr. Mike Laskowski
• Idaho State University, Dr. Chris Daniels
• Boise State University, Dr. Julia Oxford
• Cell Signaling theme

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Cell Signaling

• How Cells Communicate with Each Other
• How the Cell Membrane Communicates with the
  Inside of the Cell
  
• Room for Everybody

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• Overview of the BRIN Program
• Bioinformatics
• Research Facilities Enhancement
• Student Opportunities
• Faculty Development
• Outreach Activities
• Collaborative Efforts

Drs. Robert Heckendorn and James Foster, UI
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Statewide Bioinformatics Access

• Hardware and user support (2.0 FTEs)
• Statewide access to research and teaching
  software
  
• Module development and site visits to
  undergraduate colleges

Dr. Celeste Brown, Luke Sheneman, UI (top), BSU
bioinformatics computer lab (below)
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BioinformaticsTraining Opportunities

• Faculty and student workshops, classes and
  tutorials
  
• Dedicated classrooms at ISU, BSU and UI
• Annual statewide workshop
• Masters/Ph.D. program in Bioinformatics
  Computational Biology

Dr. Alok Bhushan teaching bioinformatics
workshop, ISU
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• Overview of the BRIN Program
• Research Facilities Enhancement
• Student Opportunities
• Faculty Development
• Outreach Activities
• Collaborative Efforts

NMR Facility, UI
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State-of-the-art Research Facilities

• To provide greater access to technology
• Training of faculty and students
• Salary support for technical expertise
• Education outreach

Dr. Bill Fusco, manager of the Microarray
Facility, UI
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Core Facilities
Nuclear Magnetic Resonance Facility, UI
Micoarray Facility, UI Proteomics Facility, BSU
Animal Care Facility, Boise VA Molecular Core
Facility, ISU
Moscow
Boise
Pocatello
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Overview of the BRIN Program Bioinformatics Rese
arch Facilities Enhancement Student Opportunities
Faculty Development Outreach Activities Colla
borative Efforts
UI undergraduate student
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Pipeline to Graduate Education

• K-12
• Magic Valley Science Expo
• 6-9th grade Migrant Minority Youth Math/Science
  Camp
  
• 11th and 12th grade UDoc
• Undergraduate
• Scholars Program
• Fellows Program
• Employed as lab staff
• Sponsoring science club activities
• Graduate
• Assistantships
• Neuroscience and Bioinformatics and Computational
  Biology Degrees

Sorcha Cusak, graduate student, BSU
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Undergraduate Opportunities Fellows Program

• 28 Students 2002
• 47 Students 2003
• 33 Students - 2004
• Disadvantaged background
• Students from all 9 institutions
• Didactic and colloquium supplements
• 100 Applicants
• Pool of graduate school applicants

Erin Douthit, former BRIN Fellow, current M.S.
student, UI
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Overview of the BRIN Program Bioinformatics Rese
arch Facilities Enhancement Student Opportunities
Faculty Development Outreach Activities Colla
borative Efforts
Dr. Troy Rohn, BSU
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Faculty DevelopmentRecruitment and Startup Funds

• Recruiting biomedical researchers to enhance
  current and future research areas
  
• Startup funds
• Bridge salary support transferring to state
  supported positions

Dr. Kathy Magnusson, UI
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Faculty DevelopmentSeed Grants

• Up to 25,000 per award
• Junior researchers working towards their first
  R01
  
• Mid-career researchers seeking a second area of
  funding
  
• 26 Awards Statewide
• 11 at ISU
• 2 at BSU
• 13 at UI

Dr. Chris Daniels, ISU, with BRIN funded students
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Faculty DevelopmentGrant Writing Skills

• August 2002, 2003 grant writing workshops
• ISU interactive grant writing program
• External reviewers
• Mock panel review

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Agenda
Overview of the BRIN Program Bioinformatics Rese
arch Facilities Enhancement Student Opportunities
Faculty Development Outreach Activities Colla
borative Efforts
Margaret Ricci, Outreach Coordinator, UI
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Undergraduate Outreach Steering Committee
College Steering Committee Drs. Dwight Wray (BYU-
I), Dan Nogalas (NNU), Mark Sugden (CSI), Ann
Koga (Alb.), Bob Murray (NIC), Jane Finan (LCSC)
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Undergraduate Outreach

• Site visits to discuss needs and interest
• Development of individualized programs
• Student sponsorships
• Equipment purchases
• Faculty buyout to do research
• Travel grants to research conferences
• Inclusion in Annual Conference
• Representation on the State Steering Committee

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Agenda
Overview of the BRIN Program Bioinformatics Rese
arch Facilities Enhancement Student Opportunities
Faculty Development Outreach Activities Colla
borative Efforts
Laboratory of Dr. Julie Oxford, BSU
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Research Conference, August 2004, Pocatello

• 180 Participants from all 9 member institutions
• UG Poster Presentation
• Graduate Student Presentations
• Recognition Banquet
• Bioinformatics Workshop
• Grant Writing Workshop
• External Advisory Committee and Steering
  Committee meetings

Undergraduate Fellows Poster Presentation at
August 2002 Research Conference, Moscow, ID
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WAMIN Research Consortium

• Regional cooperation
• Affiliate faculty status at UW
• Electronic networking
• Grant review cooperative
• New directions for the BRIN Consortium

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Western BRIN Research Consortium

• New NIH Multi-state Telecommunications grant
• Lariat - 10M over three years
• Goal To build Research Capability Through High
  Speed Access to I-2

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BRIN Accomplishments

• Research Programs at UI, ISU, and BSU
• State Theme Cell Signaling

Research Core Facility Network
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New NIH Grants to Idaho

• 20/23 New NIH Grants received Support from BRIN
• 11.5 M 2003-04
• Idaho Leads USA in New NIH Support, Doubling in
  Last Three Years

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BRIN Accomplishments (2001-04)

• Faculty Researchers 139
• Graduate Students 44
• Undergraduate Research 199
• ___
• Total 382

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INBRE IDEA Network for Biomedical Research
Excellence

• 16.1M over five years
• Create a Statewide Research Network
• Include Undergraduate Colleges
• Create an Educated Workforce
• Build a Sustainable Infrastructure

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Network Under INBRE
University of Idaho PhD Granting/Research Intensi
ve Univ.
Idaho State University PhD Granting/Research Inte
nsive Univ.
Outreach Colleges College of Southern Idaho (2 yr
) North Idaho College (2 yr) Lewis-Clark State C
ollege (4 yr)
Brigham Young Univ. - Idaho (4 yr)
Network Research Partners Boise State Univ. Albe
rtson College of Idaho Northwest Nazarene Univ.
Boise VA Medical Center Mountain States Tumor and
Medical Research Inst.
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Cores under INBRE

• Administrative
• Bioinformatics
• Research
• Outreach

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Administrative Core

• Core Director Michael Laskowski

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Idaho INBRE Program
External Advisory Committee
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INBRE Bioinformatics

• James A. Foster
• Director, Bioinformatics Core

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Bioinformatics Goals for INBRE

• Redirect UI Core mission graduate education
  research
  
• Build BSU Core directed at research and
  education
  
• Enhance education/use at all 10 Colleges

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Idaho INBRE Program

• Research Core
• Carolyn Hovde Bohach

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INBRE will maintain and support access to the
infrastructure built by BRIN

• Core Facilities full-time expert technical
  assistance
  
• Faculty Development
• Mentoring
• Grant Development
• Graduate Student and Postdoctoral Fellows
  support
  

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Pipeline Programs
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Developing an Educated Workforce-Biotechnology

• Creation of BIO Idaho
• Idahos First Statewide Bioscience Association

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Mission of BIO Idaho

• Primary mission is to enhance the development of
  the bioscience infrastructure in Idaho, promoting
  the creation and retention of the states
  intellectual capital by focusing on the process
  of transferring promising technology into the
  private sector for investment and development.

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BIO Idaho Member Constituency

• Universities and Colleges
• Business Leaders and Corporations
• National Labs
• State Labs
• Private Industry R D Labs
• Economic Development Agencies
• Developing Bioscience Companies
• Individual Entrepreneurs

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How Does BIO Idaho Help Idaho?

• New industry from Idahos existing infrastructure
  strengths
  
• Attract investment capital
• Critical mass in the biosciences
• Enhanced education stronger
  university faculties and facilities
  
• Vibrant entrepreneurial culture

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Putting It All Together

• Primary Goal of INBRE Sustainable Biomedical
  Research
  
• Jobs in Biomedical Research and Education
• Idahos Economic Future

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Keep Smilin