Biochemistry of Behavior Griffith Lab

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Biochemistry of Behavior Griffith Lab
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Neuronal Circuits
Behavior
Molecules
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(No Transcript)
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Behavior
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Courtship Behavior
Following vision, olfaction
Tapping gustation, touch
Wing Extension hearing
Licking gustation, touch
Attempted Copulation touch
Copulation
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Classic Courtship ConditioningSiegel and Hall,
1979
test within 5 min of training
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15
30
45
60

Time (min)
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Cellular Mechanisms
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Images Vivian Budnik et al.
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Chronic Modulation of CaMKII Activity Occludes
Plasticity of Intrinsic Properties
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Biochemistry
active
inactive
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Eag Binds and Activates CaMKII
Cmg
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Camguk Binds and Inactivates CaMKII
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Genetic Circuit Bashing
Courtship Learning
Signaling CaMKII Ion Channels Eag
Shal Scaffolds Cmg
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Bassine Penthousex6-3125griffith_at_brandeis.edu