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RCS 6080 Medical and Psychosocial Aspects of Rehabilitation Counseling

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Lupus - Anatomy ... Lupus Anatomy (joints) Almost everyone with SLE has joint pain or inflammation. ... Lupus Anatomy. Lupus can also affect the nervous system ... – PowerPoint PPT presentation

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Title: RCS 6080 Medical and Psychosocial Aspects of Rehabilitation Counseling


1
RCS 6080 Medical and Psychosocial Aspects of
Rehabilitation Counseling
  • Rheumatic Diseases

2
Rheumatoid Arthritis
  • The prevalence of rheumatoid arthritis in most
    Caucasian populations approaches 1 among adults
    18 and over and increases with age, approaching
    2 and 5 in men and women, respectively, by age
    65
  • The incidence also increases with age, peaking
    between the 4th and 6th decades
  • The annual incidence for all adults has been
    estimated at 67 per 100,000

3
Rheumatoid Arthritis
  • Both prevalence and incidence are 2-3 times
    greater in women than in men
  • African Americans and native Japanese and Chinese
    have a lower prevalence than Caucasians
  • Several North American Native tribes have a high
    prevalence
  • Genetic factors have an important role in the
    susceptibility to rheumatoid arthritis

4
Rheumatoid Arthritis
  • Rheumatoid arthritis is an autoimmune disease in
    which the normal immune response is directed
    against an individual's own tissue, including the
    joints, tendons, and bones, resulting in
    inflammation and destruction of these tissues
  • The cause of rheumatoid arthritis is not known
  • Investigating possibilities of a foreign antigen,
    such as a virus

5
Rheumatoid Arthritis
  • Description
  • Morning stiffness
  • Arthritis of 3 or more joints
  • Arthritis of hand joints
  • Symmetric arthritis
  • Rheumatoid nodules
  • Serum rheumatoid factor
  • Radiographic changes
  • A person shall be said to have rheumatoid
    arthritis if he or she has satisfied 4 of 7
    criteria, with criteria 1-4 present for at least
    6 weeks

6
Rheumatoid Arthritis
  • Rheumatoid arthritis usually has a slow,
    insidious onset over weeks to months
  • About 15-20 of individuals have a more rapid
    onset that develops over days to weeks
  • About 8-15 actually have acute onset of symptoms
    that develop over days

7
Functional Presentation and Disability of RA
  • In the initial stages of each joint involvement,
    there is warmth, pain, and redness, with
    corresponding decrease of range of motion of the
    affected joint
  • Progression of the disease results in reducible
    and later fixed deformities
  • Muscle weakness and atrophy develop early in the
    course of the disease in many people

8
Complications of Rheumatoid Arthritis
  • Complications include
  • Carpal tunnel syndrome, Bakers cyst, vasculitis,
    subcutaneous nodules, Sjögrens syndrome,
    peripheral neuropathy, cardiac and pulmonary
    involvement, Feltys syndrome, and anemia

9
Treatment and Prognosis
  • Medications
  • NSAIDS - Usually, only one such NSAID should be
    given at a time. Can be titrated every two weeks
    until max dosage or response is obtained. Should
    try for at least 2 to 3 wk before assuming
    inefficacy.
  • Slow acting - Generally, if pain and swelling
    persist after 2 to 4 mo of disease despite
    treatment with aspirin or other NSAIDs, can add a
    slow-acting or potentially disease-modifying drug
    (eg, gold, hydroxychloroquine, sulfasalazine,
    penicillamine) Methotrexate, an
    immunosuppressive drug is now increasingly also
    used very early as one of the second-line
    potentially disease-modifying drugs.

10
Medications
  • Corticosteroids offer the most effective
    short-term relief as an anti-inflammatory drugs.
    Long-term though improvement diminishes.
    Corticosteroids do not predictably prevent the
    progression of joint destruction, although a
    recent report suggested that they may slow
    erosions. Severe rebound follows the withdrawal
    of corticosteroids in active disease.
  • Immunosuppressive drugs These drugs (eg,
    methotrexate, azathioprine, cyclosporine) are
    increasingly used in management of severe, active
    RA. They can suppress inflammation and may allow
    reduction of corticosteroid doses. Major side
    effects can occur, including liver disease,
    pneumonitis, bone marrow suppression, and, after
    long-term use of azathioprine, malignancy.

11
Treatment
  • Surgery video
  • Removal of inflamed synovium
  • Arthroplasty
  • Physical therapy

12
Vocational Implications of Rheumatoid Arthritis
  • Need to make frequent assessments of the persons
    functional ability as the disease progresses in
    order to provide realistic goals and support
  • Motor coordination, finger and hand dexterity,
    and eye-hand-foot coordination are adversely
    affected
  • Vocational goals dependent on fine, dexterous, or
    coordinated movement of the hand are not ideal

13
Vocational Implications of Rheumatoid Arthritis
  • Most jobs requiring medium to heavy lifting are
    not desirable
  • Activities such as climbing, balancing, stooping,
    kneeling, standing, or walking are hampered
  • Extremes of weather or abrupt changes in
    temperature should be avoided indoor controlled
    climate better

14
Lupus
  • Systemic lupus erythematosus (also called SLE, or
    lupus) is an autoimmune disease of the body's
    connective tissues. Autoimmune means that the
    immune system attacks the tissues of the body. In
    SLE, the immune system primarily attacks parts of
    the cell nucleus.
  • SLE affects tissues throughout the body. Five
    times as many women as men get SLE. Most people
    develop the disease between the ages of 15 and
    40, although it can show up at any age.

15
Lupus - Anatomy
  • SLE causes tissue inflammation and blood vessel
    problems pretty much anywhere in the body. SLE
    particularly affects the kidneys. The tissues of
    the kidneys, including the blood vessels and the
    surrounding membrane, become inflamed (swollen),
    and deposits of chemicals produced by the body
    form in the kidneys. These changes make it
    impossible for the kidneys to function normally.
  • Note the granular appearance of the cortex of
    these lupus affected kidneys its across the
    entire surface of both kidneys suggesting a
    chronic condition.

16
Lupus Anatomy (cont).
  • The inflammation of SLE can be seen in the
    lining, covering, and muscles of the heart. The
    heart can be affected even if you are not feeling
    any heart symptoms. The most common problem is
    bumps and swelling of the endocardium, which is
    the lining membrane of the heart chambers and
    valves.
  • SLE also causes inflammation and breakdown in the
    skin. Rashes can appear anywhere, but the most
    common spot is across the cheeks and nose.
  • People with SLE are very sensitive to sunlight.
    Being in the sun for even a short time can cause
    a painful rash. Some people with SLE can even get
    a rash from fluorescent lights.
  • Rashes caused by SLE are red, itchy, and painful.
    The most typical SLE rash is called the butterfly
    rash, which appears on the face particularly
    the cheeks and across the nose. SLE can also
    causes hair loss. The hair usually grows back
    once the disease is under control.

17
Lupus Anatomy (joints)
  • Almost everyone with SLE has joint pain or
    inflammation. Any joint can be affected, but the
    most common spots are the hands, wrists, and
    knees. Usually the same joints on both sides of
    the body are affected. The pain can come and go,
    or it can be long lasting. The soft tissues
    around the joints are often swollen, but there is
    usually no excess fluid in the joint. Many SLE
    patients describe muscle pain and weakness, and
    the muscle tissue can swell.

18
Lupus Anatomy
  • Lupus can also affect the nervous system causing
    headaches, seizures, and organic brain syndrome.
  • It can cause anemia due to blood loss or from the
    kidney disease (it does not directly effect the
    red blood cells).
  • Pregnancy the chances of miscarriage, premature
    birth, and death of the baby in the uterus are
    high.

19
Seronegative Spondyloarthropathy
  • Consist of a group of related disorders that
    include Reiter's syndrome, ankylosing
    spondylitis, psoriatic arthritis, and arthritis
    in association with inflammatory bowel disease
  • Occurs more age at diagnosis in the third decade
    and a peak commonly among young men, with a mean
    incidence between ages 25 and 34
  • The prevalence appears to be about 1
  • The male-to-female ratio approaches 4 to 1 among
    adult Caucasians
  • Genetic factors play an important role in the
    susceptibility to each disease

20
Seronegative Spondyloarthropathy
  • The cause is unclear, but there is strong
    evidence that the initial event involved
    interaction between genetic factors and
    environment factors, particularly bacterial
    infections
  • Reiters syndrome may follow a wide range of GI
    infections
  • Bowel inflammation has been implicated in the
    pathogenesis of endemic Reiters syndrome,
    psoriatic arthritis, and ankylosing spondylitis

21
Seronegative Spondyloarthropathy
  • The spondyloarthropathies share certain common
    features, including the absence of serum
    rheumatoid factor, an oligoarthritis commonly
    involving large joints in the lower extremities,
    frequent involvement of the axial skeleton,
    familial clustering, and linkage to HLA-B27
  • These disorders are characterized by inflammation
    at sites of attachment of ligament, tendon,
    fascia, or joint capsule to bone (enthesopathy)

22
Sacroiliitis
  • Sacroiliitis is an inflammation of the sacroiliac
    joint.
  • Symptoms usually include a fever and reduced
    range of motion.
  • Picture on the bottom right shows an individual
    with sacroiliitis and Ankylosing Spondylitis.
    The arrows point to the inflamed and narrowed SI
    joints. They are white due to bony sclerosis
    around the joints

23
Ankylosing Spondylitis
  • Chronic disease that primarily affects the spine
    and may lead to stiffness of the back. The joints
    and ligaments that normally permit the back to
    move become inflamed. The joints and bones may
    grow (fuse) together.
  • The effects are inflammation and chronic pain and
    stiffness in the lower back that usually starts
    where the lower spine is joined to the pelvis or
    hip.
  • Diagnosis is made through (a) medical history
    including symptoms, (b) X-rays, and possibly (c)
    blood tests for HLA-B27 gene

24
Ankylosing Spondylitis
  • Treatment options
  • With early diagnosis and treatment, pain and
    stiffness can be controlled and may reduce
    fusing. In women, AS is usually mild and hard to
    diagnose.
  • Exercise
  • Medications NSAIDs, Sulfasalazine
  • Posture management
  • Self-help aids
  • Surgery

25
Reiter's Syndrome
  • Arthritis that produces pain, swelling, redness
    and heat in the joints. It can affect the spine
    and commonly involves the joints of the spine and
    sacroiliac joints. It can also affect many other
    parts of the body such as arms and legs. Main
    characteristic features are inflammation of the
    joints, urinary tract, eyes, and ulceration of
    skin and mouth.
  • The symptoms are fever, weight loss, skin rash,
    inflammation, sores, and pain.

26
Reiter's Syndrome
  • Reiter's often begins following inflammation of
    the intestinal or urinary tract. It sets off a
    disease process involving the joints, eyes,
    urinary tract, and skin. Many people have
    periodic attacks that last from three to six
    months. Some people have repeated attacks, which
    are usually followed by symptom-free periods.
  • Diagnosis is made through a physical exam, skin
    lesions, and a test for the HLA-B27 gene

27
Reiter's Syndrome
  • For different parts of the body, different
    treatments are used
  • Medications NSAIDs, antibiotics, topical skin
    medications
  • Eye drops
  • Joint protection
  • Various symptoms are treated by healthcare
    specialists

28
Psoriatic Arthritis
  • Causes pain and swelling in some joints and scaly
    skin patches on some areas of the body.
  • The symptoms are
  • About 95 of those with psoriatic arthritis have
    swelling in joints outside the spine, and more
    than 80 of people with psoriatic arthritis have
    nail lesions. The course of psoriatic arthritis
    varies, with most doing reasonably well.
  • Silver or grey scaly spots on the scalp, elbows,
    knees and/or lower end of the spine.
  • Pitting of fingernails/toenails
  • Pain and swelling in one or more joints
  • Swelling of fingers/toes that gives them a
    "sausage" appearance.

29
Psoriatic Arthritis
  • Diagnosis may involve X-rays, blood tests, and
    joint fluid tests.
  • Treatment options
  • Skin care
  • Light treatment (UVB or PUVA)
  • Corrective cosmetics
  • Medications glucocorticoids, NSAIDs, DMARDs
    (disease-modifying anti-rheumatic drugs)
  • Exercise
  • Rest
  • Heat and cold
  • Splints
  • Surgery (rarely)

30
Inflammatory Bowel Disease
  • IBD consists of two separate diseases that cause
    inflammation of the bowel and can cause arthritis
    or inflammation in joints
  • Crohn's Disease involves inflammation of the
    colon or small intestines.
  • Ulcerative Colitis is characterized by ulcers and
    inflammation of the lining of the colon.

31
Inflammatory Bowel Disease
  • The amount of the bowel disease usually
    influences the severity of arthritis symptoms.
    Other areas of the body affected by inflammatory
    bowel disease include ankles, knees, bowel,
    liver, digestive tract, skin, eyes, spine, and
    hips.
  • Treatment options
  • Diet
  • Exercise
  • Medication Corticosteroids, Immunosuppressants,
    NSAIDs, Sulfasalazine
  • Surgery

32
Functional Presentation and Disability of the
Spondylarthropathies
  • When the axial skeleton is involved, the initial
    symptom is morning stiffness and lower back pain
  • As the disease worsens, there is progressive
    diminution of motion of the spine
  • Eventually, the sacroiliac joints, lumbar,
    thoracic, and cervical spine become fused
  • At this stage, the spine is no longer painful,
    but the person has lost all ability to flex or
    rotate the spine and generally develops a
    hunched-over posture with fused flexion of the
    cervical spine and flexion contracture of the
    hips to compensate for the loss of the lordosis
    curvature in the lumbar spine

33
Functional Presentation and Disability of the
Spondylarthropathies
  • The joints where the ribs attach to the vertebrae
    are also affected, and chest expansion and lung
    volume are decreased
  • Frequently, peripheral joints are involved, and
    the pattern is usually asymmetric oligoarthritis
    involving primarily the large or medium joints,
    including the hips, knees, and ankles
  • Rarely are smaller joints or the joints in the
    upper extremities involved
  • Loss of motion of the spine or pain in the spine
    with motion generally affects a person's mobility

34
Functional Presentation and Disability of the
Spondylarthropathies
  • Walking remains unimpaired unless the hips and
    knees are affected
  • Frequent stooping and bending become impossible
  • A person with ankylosing spondylitis typically is
    able to continue vocational activity despite
    progressive stiffness, unless it requires
    significant back mobility or physical labor

35
Vocational Implications of the Spondylarthropathie
s
  • The person should be considered for vocational or
    professional education as resources and interests
    dictate
  • A stiff back will limit the persons rotation and
    flexion so that overall dexterity may be affected
  • Tasks that require reaching or bending will be
    difficult and lifting over 10-15 pounds may cause
    increased back pain
  • Climbing and balancing skills, stooping, and
    kneeling may be tolerated initially but become
    difficult as the disease worsens
  • Need time to stretch spine frequently

36
Degenerative Joint Disease(Osteoarthritis)
  • Most common rheumatic disease and is
    characterized by progressive loss of cartilage
    and reactive changes at the margins of the joint
    and in the subchondral bone
  • The disease usually begins in ones 40s
  • Prevalence increases with age and the disease
    becomes almost universal in individuals aged 65
    and older
  • Primarily affects weight-bearing joints such as
    the knees, hips, and lumbrosacral spine

37
Degenerative Joint Disease
  • Cause is unclear
  • Considered to be a wear and tear arthritis and
    is thought to occur as a consequence of some
    earlier damage or overuse of the joint
  • Obesity is frequently associated with it
  • Genetic factors play a role in the development
    that is sex-influenced and dominant in females,
    resulting in an incidence 10 times greater than
    in men
  • The final outcome is full-thickness loss of
    cartilage down to bone

38
Degenerative Joint Disease
  • In early disease, pain occurs only after joint
    use and is relieved by rest
  • As the disease progresses, pain occurs with
    minimal motion or even at rest
  • Nocturnal pain is commonly associated with severe
    disease

39
Functional Limitations and Degenerative Joint
Disease
  • Limited use of the involved joint
  • Walking and transfer activities may be impaired
  • Generally, ADLs will not be significantly impaired

40
Treatment and Prognosis of Degenerative Joint
Disease
  • Meds
  • Early PT/exercises
  • Heat/cold therapy
  • Joint protection
  • Surgery
  • Osteoarthritis is a slowly progressive disease
  • The eventual outcome is complete destruction of
    the joint, and ultimately surgical intervention
    is required

41
Vocational Implications and Degenerative Joint
Disease
  • Can continue in present job unless it requires
    dexterous or heavy use of the involved joint
  • Heavy lifting should be avoided
  • Light to medium work should be possible
  • Climbing, balancing skills, stooping, and
    kneeling may be impaired
  • Returning to work after surgery requires
    intensive postop rehab and continued exercise to
    maintain muscle strength
  • Most individuals are able to sustain gainful
    employment and a normal level of activity

42
Additional Resources and Information from the Web
  • American College of Rheumatology
    (www.rheumatology.org)
  • National Institute of Arthritis and
    Musculoskeletal and Skin Diseases
    (www.niams.nih.gov)
  • Arthritis Foundation (www.arthritis.org)
  • Arthritis National Research Foundation
    (www.curearthritis.org)
  • Info on Juvenile RA (http//www.nlm.nih.gov/medlin
    eplus/juvenilerheumatoidarthritis.html)
  • Spondylitis Association of America
    (www.spondylitis.org)
  • Arthritis.com Latest Arthritis Information
    Community (www.arthritis.com)
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