Cardiac Web

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Cardiac Web
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Myocardial Oxygen Supply and Demand (fig 16.4)
Blood substrate
contractility
A-VO2
MVO2 Demand
MVO2 Supply
Heart rate

Coronary flow distribution
Wall tension
?
Coronary flow
Vent pressure
Vent volume
Coronary vascular resistance
Aortic pressure
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Coronary Artery Disease
ANS Problems? Hypertension?
Thrombus forms and becomes Embolism
Reduced capacity to deliver blood to myocardium
Vasospasm
Increased demand for O2 that cannot be met
Sudden loss of O2
Ischemia
Ischemia
Unstable Angina
Stable Angina
Injury
Injury
Infarction
Infarction
Myocardial Infarction (MI)
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Chest Pain
Ischemic
ECG
ST Elevation
No ST Elevation
Biochemical Markers
R/I Non Q Wave MI
R/I Q Wave MI
R/O MI Unstable Angina?
Complicated (Unstable) vs. Uncomplicated
(Stable) Low Risk vs. High Risk
Exercise ?? Role in different patients
Evaluation, Treatment, Prevention, Rehabilitation
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Arrhythmia
Coronary Arteries
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Arrhythmia
Coronary Arteries
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From Ventilation to Respiration
Reduce ms force reduce pressure gradients for
airflow
Impaired Air Flow
Hyperinflation
Reduced Ventilation
Reduced Alveolar Ventilation
Reduced Alveolar surface area increased wall
thickness
Reduced Pressure Gradients between Alveoli and
Blood O2 CO2
Reduced VQ Matching
Hypercarbia Hypoxia
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Impairment Interactions
PaCO2
Respiration
Oxygen Carrying Capacity
PaO2
Alveoli Health
RBC
Alveolar (PAO2)
Alveolar (PACO2)
Renal Function
Pump Effectiveness
Pulmonary Blood Flow
Alveolar Ventilation
Arrhythmia
Ventilation
Cardiac Effects
Breathing Mechanics