Adding a Second Mood Stabilizer vs Adding an Antidepressant

1
Adding a Second Mood Stabilizer vs Adding an
Antidepressant
25
Hamilton Rating Scale for Depression
Two mood stabilizers Mood stabilizer
and paroxetine
(16)
20
Young Mania Rating Scale Two mood
stabilizers Mood stabilizer and
paroxetine
(11)
(15)
15
(11)
(12)
Score
(11)
(11)
(11)
10
(11)
(11)
(11)
n 27
(10)
(10)
(10)
5
0
Baseline
1
2
3
4
5
6
Duration of Treatment (weeks)
Parenthetical numbers indicate numbers of the
remaining 27 subjects, but the data points
include imputed (last observation carried
forward) data on dropouts. Medications used are
valproate lithium Young LT, et al. Am J
Psychiatry. 2000157124-126.