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Ion Channels defined

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How is the internal energy in a system containing a large number of particles (N) ... Na:K ATPase, a Stoichiometric Transporter. Moves 3Na out and 2K in per ATP. ... – PowerPoint PPT presentation

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Title: Ion Channels defined


1
Ion Channels defined
2
Literature Grows
3
Early Models
4
KcsA K channel structures
5
Gulbis structure
6
3 Kinds of nervous signal
7
AP recording
8
HH AP
9
Single Na Channels
10
State diagram for Na Ch
11
Early Models
12
Ion channel disease 1
13
Ion channel disease 2
14
Ionic current moving ions
15
Ludwig Boltzmann
Question How is the internal energy in a system
containing a large number of particles (N)
distributed among the particles?
Ans.there will be more particles with low
energy (U) than with high
Boltzmann constant (R/Na )
N
N(U) A exp -(U/ kbT)
n1
n2
U
U1
U2
16
Biophysics Nernst Potential
17
Current-Voltage Relations
E is potential in volts
18
Membrane Capacitance
19
Equivalent Circuits
20
AP recording
21
Flux coupling in a long pore
Force
22
KcsA K channel structures
23
Stoichiometry of a pump
24
Evolutionary tree
25
K Channel Dendrogram
26
Three Roles of ion channels
27
Electrical call to action
28
Ca channel modulation
29
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