Biologically Accurate Modeling of Mouse Brain Requires Biologically Accurate Networks

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Biologically Accurate Modeling of Mouse Brain
Requires Biologically Accurate Networks
Dataset taken with the Serial Block Face SEM
developed by Winfried Denk, Max Planck Institute,
Heidelberg
Illustration courtesy of Stephen Smith, Stanford
University
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Traced trajectories of neuronal processes through
SBF-SEM volumetric data
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Analogous scans of heavy-element (osmium
tetroxide) stained tissue imaged using light
microscopy
20X (0.7 NA) 100?m bar
60X (1.4 NA) 50?m bar