Center For Vision Reseach SUNY Upstate Medical University

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Center For Vision ReseachSUNY Upstate Medical
University
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Principal Investigators

• R. Barlow Metabolic Stress in the Retina
• P. Calvert Subcellular Localization/Dynamics in
  Cilia
• B. Knox Visual Pigment Expression and Function
• F. Pignoni Eye Specification and Development
• E. Solessio Metabolism/Function of Diabetic
  Retina
• A. Viczian Differentiation of Retinal Stem Cells
• M. Zuber Genetic Regulation of Eye Formation
• D. Tso Function of Visual Cortex and Retina
• B. Farrell Stereopsis and Orientation
• B. Motter Visual Crowding and Attention

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Model Systems

• R. Barlow Transgenic mice, primate and human
• P. Calvert Transgenic Xenopus and cell culture
• B. Knox Transgenic Xenopus and cell culture
• F. Pignoni Drosophila mutants and transgenics
• E. Solessio Transgenic mice
• A. Viczian Mouse and human embryonic stem cells
• M. Zuber Transgenic Xenopus
• D. Tso Primate and transgenic mice
• B. Farrell Human
• B. Motter Primate

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Experimental Approaches Molecular and Cellular
Biology/Electrophysiology

• R. Barlow Behavioral analysis, ERG, Multifocal
  ERG
• P. Calvert Multiphoton microscopy and live cell
  imaging
• B. Knox Live imaging, membrane protein
  expression, spectroscopy
• F. Pignoni Drosophila genetics
• E. Solessio Behavioral analysis, mass
  spectroscopy/metabolite analysis
• A. Viczian ESC culture facility
• M. Zuber Xenopus embryo manipulation, microarray
• D. Tso Functional imaging, cortical
  electrophysiology
• B. Farrell Psychophysics
• B. Motter Electrophysiology

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CVR Philosophy

• CVR Research Meeting every week-research
  presentations by students, postdocs and faculty
• Common mentoring of students and postdocs by CVR
  faculty
• Hands-on mentoring of junior faculty-both grants
  and project development
• Shared labs and space
• Shared common equipment with co-ownership
• Formal and informal co-investigators on grants
• Existing collaborations with many labs outside NY

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We bring to the table

• Transgenic technology, genetic manipulation and
  functional analytical tools
• Scaffolding ideas- Metabolic dysfunction and
  retinal disease- Mutant characterization using
  live imaging- Transcription network
  characterization in stem cell therapy and diseases