Title: Bioterrorism Preparedness
1Bioterrorism Preparedness
- Daniel W. Saylak, D.O., FACOFP
- Senior Medical Officer
- Texas-1 Disaster Medical Team
- National Disaster Medical Service
2The United States of America Responds to
Disasters at Numerous Levels
3Combination Civilian/Military Agencies
4Disaster Preparedness
5Bioterrorism
- Does the TV series 24 represent the threats?
6A University of Arizona researcher has created a
method and map that shows the relative level of
threat of bioterrorism in 132 major cities in the
United States. The map displays the level of risk
based critical industries, ports, railroads,
population, natural environment and other
factors.
7What is Bioterrorism?
- The history of bioterrorism goes back as far
as human warfare, in which there have always been
efforts to use germs and disease as weapons. In
the late 20th century, violent non-state actors
began seeking to acquire or develop biological
agents to use in attacks on civilians. The
reported risk has led the U.S. government to
expend immense resources for biodefense in the
early part of the 21st century.
8Class A Biological Diseases
- Bioterrorism refers to the intentional release of
toxic biological agents to harm and terrorize
civilians, in the name of a political or other
cause. The U.S. Center for Disease Control has
classified the viruses, bacteria and toxins that
could be used in an attack. Category A Biological
Diseases are those most likely to do the most
damage. They include - Anthrax (Bacillus anthracis)
- Botulism (Clostridium botulinum toxin)
- The Plague (Yersinia pestis)
- Smallpox (Variola major)
- Tularemia (Francisella tularensis)
- Hemorrhagic fever, due to Ebola Virus or Marburg
Virus
9A Brief History of Bioterrorism
- Sixth Century B.C.One of the earliest
reported uses of bioterrorism. Assyrians poison
enemy wells with rye ergot, a fungus that causes
convulsions if ingested.1346Plague breaks out
in the Tartar army during its siege of Kaffa (at
present-day Feodosia in Crimea). Attackers hurl
the corpses of plague victims over the city
walls, causing an epidemic that forces the city
to surrender. Some infected Kaffa residents who
left the city may have inadvertently started the
Black Death pandemic. 1754During the French
and Indian wars, it's suspected British forces
distribute smallpox-laden blankets to native
American Indians who were loyal to the French.
1870German scientist Robert Koch proves that
microorganisms cause infectious diseases by
injecting anthrax spores into mice. The mice
contract the disease.1882In France, Louis
Pasteur develops the first successful vaccine to
prevent anthrax in animals.
10Bioterrorism 1900 - 2009
- This century biological and chemical warfare has
reached new heights of ingenuity.1910-20 On
April 22, 1915, the Germans used poison gas for
the first time at Ypres in Belgium. By 1918, one
in four shells on the western front was a gas
shell, and its use resulting in more than one
million casualties and more than 100,000
deaths.1930-40 Japan reportedly used plague and
other bacteria in the war against China in the
1930s and 1940s.1983-88 More recently, there is
evidence Iraq used chemical weapons extensively
during the Iran-Iraq war between 1983 and 1988
and subsequently against the Kurds.The threat
now that most countries have agreed to destroy
military stockpiles of chemical and biological
weapons, the biggest remaining threat is
terrorism.1984 In 1984, a safe house belonging
to the German Red Army Faction, a militant group,
was reportedly uncovered in Paris, France.1993
The bomb that damaged the World Trade Center in
New York in 1993 reportedly also contained
cyanide, but the chemical apparently evaporated
in the explosion.1994 In 1994 two members of a
religious cult in Oregon successfully used
salmonella to poison the salad bars of local
restaurants in an attempt to affect the outcome
of local elections. More than 700 people were
believed to be affected, though none were
apparently killed, and the reason for the
outbreak was not uncovered for a year.1995 The
series of Sarin gas attacks made on the Tokyo
subway system by a cult in March 1995 that killed
a dozen people and injured thousands brought the
use of chemical and biological weapons to
international attention. Inside the safe house an
improvised laboratory was said to have been found
containing flasks of deadly botulism toxin.
11Pulling In The Reins
- Although several countries are suspected to
retain some chemical or biological weapons
capabilities, nearly all have formally agreed to
renounce their military use.Even as early as
ancient times, the Greeks and Romans condemned
the use of poison as a violation of the rules of
war, though they continued to use it.1925 After
World War I, the Geneva Protocol of 1925 outlawed
the use of both chemical and biological weapons
in war, but countries were unable to agree on a
treaty to ban stockpiles.1956 In 1956 Marshal
Zhukov announced to the Soviet Congress that
chemical and biological warfare weapons would be
used as weapons of mass destruction in future
warsThis caused the US to renew its own
programs, but in 1969, US President Nixon ordered
the termination of all research on biological
warfare and the disarmament of all such
weapons.This outlawed the production,
stockpiling and use of biological weapons. In
July 1995, however, Iraq admitted that it had
tried to build up stocks of biological weapons
after UN inspectors found large amounts of
anthrax, botulinum and other toxins.1993 In
January 1993 a ban on the production, stockpiling
and use of chemical weapons - The Chemical
Weapons Convention was signed by 130 countries.
Iraq has yet to sign this ban, however, and of
the 165 countries which have now signed, 62 have
yet to ratify the agreement. The current Gulf
crisis stems from UN Security Council resolution
687, which calls for the elimination of Iraq's
weapons of mass destruction.1975 The Biological
and Toxin Weapons Convention (BWC), which
prohibits the acquisition of biological materials
for hostile purposes and armed conflict, entered
into force in 1975 and now has the participation
of 140 nations (158 nations have signed the BWC,
but only 140 of these have also ratified it).
However, there is no monitoring mechanism
associated with the BWC.
12So How do we prepare?
- Awareness
- Development of Contingency Plans
- Focus on Class A Agents
- Avoidance of High Risk Areas
- Use of mass inoculations
- Rapid delivery of pharmaceuticals
- Tested at 2009 Presidential Inauguration
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16Class A Agents
17Be Prepared