Total Synthesis

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Total Synthesis
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Condensation via Friedel-Crafts Alkylation
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Epoxide Formation
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Epoxide reaction
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Thiol Formation followed by Alkylation
End of step 1
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Diels-Alder Condensation
o-xylene
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Oxidation of Thione and Pyridine subjects
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Wacker-type oxidation
Benzoquinone
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G. W. Parshall Homogeneous Catalysis, Wiley, New
York 1980, S. 102
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Summary

• Friedel-Crafts Alkylation
• Epoxide formation
• Thiol Formation
• Diels-Alder Condensation
• Oxidation of Thione and Pyridine groups
• Wacker-type Oxidation