The Breast

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The Breast

• Major Topics for Discussion
• Mastitis (Inflammation)
• Fibrocystic change (Benign Common)
• Fibroadenoma (Benign Neoplasm)
• Invasive ductal carcinoma (Malignant)

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Breast Ductal Epithelium
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Age-Related Incidenceof Breast Pathology
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first half of menstrual cycle
second half of menstrual cycle
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Mammogram

• Irregular densities and a dominant mass in a
  patient with fibrocystic change.

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Spectrum of Histologic Changes
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Fine-Needle Aspiration Cytology
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Mammogram

• Dominant mass with smooth borders
• Fibroadenoma

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Fine-Needle Aspiration Cytology
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Fibroadenoma
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Mammogram

• Irregularly-shaped dense mass in a 65-year-old
  woman
• Ductal carcinoma

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Intraductal Carcinoma of Breast
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Aspiration Cytology
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Paget Disease of the Breast
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Lobular Carcinoma of Breast
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Invasive Lobular Carcinoma of Breast
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Path Key Words

• Acute mastitis
• Fat necrosis
• Fibroadenoma
• Fibrocystic change
• Galactocele
• Galactorrhea
• Gynecomastia
• Intraductal papillomatosis

• Invasive ductal carcinoma
• Invasive lobular carcinoma
• Medullary carcinoma
• Mucinous carcinoma
• Paget disease
• Phyllodes tumor