Biotecsur:

1

• Biotecsur
• A push for innovation through academia-industry
  partnership
• M. Susana Levy, PhD
• Manager
• RD Biotechnology
• Montevideo - 8 Diciembre 2009

2
Outline

• Company overview
• RD targets
• Biotecsur research project

3
The company

• Products for animal health
• Cattle
• Pigs
• Sheep
• Attending regional needs
• Adding value to the food chain

4
History
1934
Laboratorios Bagó
1938
Chemotécnica
Laboratorio San Jorge
1978
Instituto San Jorge Bagó
Biogénesis
1989
1994
2005
Vetia
2006
Biogénesis-Bagó
5
EXPERIENCE
6
More than 50 years working with FMDV
EXPERIENCE

• Since 1952 in the FMD vaccine market in Argentina
• Since 2000 antigen and vaccine bank in Argentina
• Since 2006 North American Foot and Mouth Disease
  Vaccine Bank (NAFMDVB) supplier

7
Production track record
EXPERIENCE

• Currently manufacturing 200 millon doses / year.
• Exports to all South American countries.
• Exports to USA and Taiwan.

8
FACILITIES
9
4 specialized plants in Argentina
FACILITIES

• FMDV manufacturing plant among the most
  important worldwide because of
• Capacity of production more than 200 millon
  multivalent doses / year (more than 700 million
  of monovalent doses)
• Technology Biosecurity level 3 (BSL 3A),
  international regulatory standards.
• Pharmaceutical products manufacturing plant
  10.000 m2 the largest in Argentina
• Manufacturing capacity 3 mill. units / year in
  orals, injectables, antibiotics, tablets and
  other specialties.
• External parasiticides and pesticides
  manufacturing plant
• New Biologics plant of about 4.000 m2 100 mill
  doses / year for viral and bacterial vaccines.

10
Vaccines Annual production capacity
FACILITIES

• FMD
• 200 million doses (multivalent)
• Rabies
• 20 millon doses
• Viral bacterial cattle
• 100 million doses

11
Human Resources
12
Human Resources
13
SCIENTIFIC BACKGROUND
14
Since 2003 Biogénesis-Bagó is part of
RIIDFAArgentinas FMD Interinstitucional
Research NetworkNational scientific
Institutions - National Animal Health Authorities
- Private Sector
SCIENTIFIC BACKGROUD
Secretaria de Ciencia , Tecnologia e Innovacion
Productivas Consejo Nacional de Investigaciones
Cientificas y Tecnicas CONICET
Secretaría de Agricultura, Ganadería, Pesca y
Alimentación
Instituto Nacional deTecnología Agropecuaria

Secretaria de Agricultura , Ganaderia, Pesca y
Alimentacion Servicio Nacional de Sanidad y
Calidad Agroalimentaria
FADEFA Fundación Argentina de Lucha contra la
Fiebre Aftosa (SRA)
IPCVA Instituto de Promoción de la Carne Vacuna
Argentina
15
RD Collaboration
SCIENTIFIC BACKGROUD

• Argentinas FMD Interinstitucional Research
  Network (RIIDFA)
• Veterinary and Agrochemical Research Center (VAR)
  - Belgium Vaccine matching Project (2006
  2007).
• European Union Research Project (2008-2011).
• Mercosur Biotechnology Platform (Biotecsur)
• Research consortia with research centres in
  Uruguay, Brasil and Paraguay (2009-2010).

16
SCIENTIFIC BACKGROUD
RD Collaboration

• National Institute for Agricultural Technology
  INTA Argentina
• Development of viral and bacterial vaccines for
  cattle (1985 1995).
• Development of Horse viral vaccines (2002-2006).
• Development of potency test for cattle viral
  vaccines, Ginea Pig model (2000 2007).
• Development of BHV-1 gene-deleted virus Vaccine
  (2002 2007).
• Recombinant FMD- VP1/interferon vaccine
  (2004-2007).

17
Biotecsur funded Research Projects

• Funds for research projects in selected priority
  areas
• Incentive for mercosur research networks
• Participation of all Mercosur countries
• Participation of academia and industry
• No limits to company size

18
Project consortium
EC Partner Dr. Arndt Benecke, Inst.Hautes Etudes
Scientifiques, FRANCIA
19
Project title
Aplication of functional genomics and other
biotechnology tools to the develpment and control
of vaccines to prevent foot-and-mouth disease in
cattle.
20
Introduce new technologies in the development and
control of foot-and-mouth disease vaccines
Objectives
21
Establish a platform for training in
biotechnologies relevant to the development and
production of veterinary vaccines
Objectives
22
Concept
Establish a regional multidisciplinary and
multisectorial research team ...
23
Concept
... to push innovation
24
Concept
25
... for a better world
26
Acknowledgments

• Biotecsur
• Ministerio de Ciencia, Tecnología e Innovacion
  Productiva, Argentina.