Title: Guidelines for using NMDP slides
1Guidelines for using NMDP slides
- The information and data in this presentation
were prepared by the National Marrow Donor
Program (NMDP). Each slide and/or information may
be used in its entirety in presentations and
publications as long as it is attributed to the
National Marrow Donor Program. - When used in presentations, NMDP slides should
retain their content, appearance and design. (For
instructions on copying the design along with the
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2Acute Lymphoblastic LeukemiaSurvival of Adult
(Age ³ 18 Years) Marrow Recipients with
Myeloablative Preparative Regimens, by Disease
Stage 19982006
Log-rank p-value lt 0.0001
First complete remission (n 195)
Second complete remission (n 179)
Advanced (n 218)
3Acute Lymphoblastic LeukemiaSurvival of Adult
(Age ³ 18 Years) PBSC Recipients with
Myeloablative Preparative Regimens, by Disease
Stage 19982006
Log-rank p-value lt 0.0001
First complete remission (n 193)
Second complete remission (n 152)
Advanced (n 157)
4Acute Lymphoblastic LeukemiaSurvival of
Pediatric (Age lt 18 Years) Marrow Recipients with
Myeloablative Preparative Regimens, by Disease
Stage 19982006
Log-rank p-value lt 0.0001
First complete remission (n 138)
Second complete remission (n 280)
Advanced (n 146)
5Acute Myelogenous LeukemiaSurvival of Adult (Age
³ 18 Years) Marrow Recipients with Myeloablative
Preparative Regimens, by Disease Stage 19982006
Log-rank p-value lt 0.0001
Second complete remission (n 264)
First complete remission (n 274)
Advanced (n 479)
6Acute Myelogenous LeukemiaSurvival of Adult (Age
³ 18 Years) PBSC Recipients with Myeloablative
Preparative Regimens, by Disease Stage 19982006
Log-rank p-value lt 0.0001
First complete remission (n 352)
Second complete remission (n 200)
Advanced (n 363)
7Acute Myelogenous LeukemiaSurvival of Pediatric
(Age lt 18 Years) Marrow Recipients with
Myeloablative Preparative Regimens, by Disease
Stage 19982006
Log-rank p-value 0.0004
Second complete remission (n 137)
First complete remission (n 98)
Advanced (n 116)
8Acute Myelogenous LeukemiaSurvival of Older
Adult (Age ³ 55 Years) Marrow and PBSC Recipients
with Non-Myeloablative Preparative Regimens, by
Disease Stage 19982006
Log-rank p-value 0.0002
Second complete remission (n 107)
First complete remission (n 239)
Advanced (n 113)
9Acute Myelogenous LeukemiaSurvival of Older
Adult (Age ³ 55 Years) Marrow and PBSC Recipients
with Myeloablative Preparative Regimens, by
Disease Stage 19982006
Log-rank p-value 0.009
First complete remission (n 82)
Second complete remission (n 44)
Advanced (n 69)
10Chronic Myelogenous LeukemiaSurvival of Adult
(Age ³ 18 Years) Marrow Recipients with
Myeloablative Preparative Regimens, by Disease
Stage 19982006
Log-rank p-value lt 0.0001
First chronic phase (n 695)
Second chronic phase / Accelerated phase (n
273)
Blast phase (n 45)
11Chronic Myelogenous LeukemiaSurvival of Adult
(Age ³ 18 Years) PBSC Recipients with
Myeloablative Preparative Regimens, by Disease
Stage 19982006
Log-rank p-value 0.004
First chronic phase (n 105)
Second chronic phase / Accelerated phase (n
117)
Blast phase (n 28)
12Inherited Immune SyndromesSurvival of Pediatric
(Age lt 18 Years) Marrow Recipients with All
Preparative Regimens, by Disease 19982006
WAS (n 48)
SCID (n 35)
13Inherited Metabolic DisordersSurvival of
Pediatric (Age lt 18 Years) Marrow Recipients with
Myeloablative Preparative Regimens, by
Disease 19982006
Hurler (n 30)
ALD / MLD (n 29)
14Myelodysplastic SyndromesSurvival of Adult (Age
³ 18 Years) Marrow Recipients with Myeloablative
Preparative Regimens, by FAB Disease
Classification 19982006
RA / RARS (n 77)
RAEB / RAEB-t (n 178)
15Myelodysplastic SyndromesSurvival of Adult (Age
³ 18 Years) PBSC Recipients with Myeloablative
Preparative Regimens, by FAB Disease
Classification 19982006
RAEB / RAEB-t (n 127)
RA / RARS (n 73)
16Myelodysplastic SyndromesSurvival of Adult (Age
³ 18 Years) Marrow and PBSC Recipients with All
Preparative Regimens, by Age at
Transplant 19982006
Log-rank p-value 0.03
Age 1854 Years (n 289)
Age ³ 55 Years (n 163)
17Myelodysplastic SyndromesSurvival of Adult (Age
³ 18 Years) Marrow and PBSC Recipients by
Conditioning Regimen 19982006
Log-rank p-value 0.11
Myeloablative (n 305)
Non-myeloablative (n 147)
18Non-Hodgkin LymphomaSurvival of Adult (Age ³ 18
Years) Transplant Recipients with
Non-Myeloablative Preparative Regimens, by
Product Type 19982006
Log-rank p-value 0.92
Marrow (n 138)
PBSC (n 254)
19Severe Aplastic AnemiaSurvival of Marrow
Recipients with All Preparative
Regimens 19982006
Log-rank p-value 0.12
Age lt 18 Years (n 218)
Age ³ 18 Years (n 166)
20Fanconi AnemiaSurvival of Pediatric (Age lt 18
Years) Marrow Recipients with Non-Myeloablative
Preparative Regimens 19982006
Fanconi anemia (n 64)