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Diagnosis: Hemorrhage from small aneurysms in the kidney due

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Diagnosis: Hemorrhage from small aneurysms in the kidney due to Poly arteritis nodosa (PAN) Poly arteritis nodosa (PAN) is a systemic vasculitis with a male: female ... – PowerPoint PPT presentation

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Title: Diagnosis: Hemorrhage from small aneurysms in the kidney due


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  • Diagnosis
  • Hemorrhage from small aneurysms in the kidney
    due to Poly arteritis nodosa (PAN)
  • Poly arteritis nodosa (PAN) is a systemic
    vasculitis with a male female ratio of 21 and a
    peak incidence in the fifth decade. Small to
    medium-sized arteries are involved by focal
    transmural inflammatory necrosis. Aneurysms with
    inflammatory destruction of the media also occur.
    The most frequently involved organs are the
    kidney, heart, lung, liver, and gastrointestinal
    tract.
  • There is no place here for Interventional
    Radiology or embolisation unless the patient is
    in deep shock and a nefrectomy is planned, and
    the patient is too ill for surgery. Embolisation
    of the renal artery might then be a rare option.
    Usually the patient is treated with high-dose
    cyclophosphamide and steroids for 6 months and is
    than continued on low-dose cyclophosphamide until
    the vasculitis is cured.
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