Cytology Weekly Cases

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Cytopathology Challenge! Weekly Cases
September 1st, 2008
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• 34 year old female, FNA of parotid
• Benign salivary gland tissue
• Pleomorphic adenoma
• Warthins tumor
• Adenoid cystic carcinoma
• Acinic cell carcinoma

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• 34 year old female, FNA of parotid
• Benign salivary gland tissue
• Pleomorphic adenoma
• Warthins tumor
• Adenoid cystic carcinoma
• Acinic cell carcinoma
• Serous cells with granular cytoplasm resembling
  normal acinic cell, but unlike the distinct
  bunches of grapes arrangement of benign acinic
  cells intermixed with ductal cells, this FNA
  shows only sheets of acinic cells.

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• FNA of submandibular saliv gland
• Benign salivary gland tissue
• Pleomorphic adenoma
• Warthins tumor
• Adenoid cystic carcinoma
• Acinic cell carcinoma

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• FNA of submandibular saliv gland
• Benign salivary gland tissue
• Pleomorphic adenoma
• Warthins tumor
• Adenoid cystic carcinoma
• Hyaline spherical globules of varying size with
  surrounding basaloid cells
• Acinic cell carcinoma

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• 45 year old female. FNA of thyroid
• Colloid
• Hyperplastic nodule
• Follicular adenoma
• Papillary thyroid carcinoma
• Hashimotos thyroiditis

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• 45 year old female. FNA of thyroid
• Colloid
• This is another photogenic representation of
  colloid.
• Hyperplastic nodule
• Follicular adenoma
• Papillary thyroid carcinoma
• Hashimotos thyroiditis

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• 49 year old female. FNA of parotid
• Benign salivary gland
• Warthins tumor
• Pleomorphic adenoma
• Mucoepidermoid carcinoma
• Adenoid cystic carcinoma

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• 49 year old female. FNA of parotid
• Benign salivary gland
• Warthins tumor
• Pleomorphic adenoma
• Mucoepidermoid carcinoma
• Squamous cells (black arrow), intermediate cells
  (green), and mucin secreting cells (yellow).
• Adenoid cystic carcinoma

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• Lung FNA
• Granulomas
• Hamartoma
• AdenoCa
• SCC
• Small cell carcinoma

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• Lung FNA
• Granulomas
• Hamartoma
• AdenoCa
• SCC
• Small cell carcinoma

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• 29 year old female. Peritoneal lavage.
• Amebiasis
• Reactive mesothelial cells
• Lymphoma
• Adenocarcinoma
• Metastatic papillary thyroid carcinoma

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• 29 year old female. Peritoneal lavage.
• Amebiasis
• Reactive mesothelial cells
• Daisy cells are normal mesothelial cells with
  multiple deep nuclear indentations. Apparently,
  this type of cell is only seen in peritoneal
  mesothelial cells.
• Lymphoma
• Adenocarcinoma
• Metastatic papillary thyroid carcinoma

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• 35 year old female, FNA of parotid
• Benign salivary gland tissue
• Pleomorphic adenoma
• Warthins tumor
• Adenoid cystic carcinoma
• Acinic cell carcinoma

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• 35 year old female, FNA of parotid
• Benign salivary gland tissue
• Pleomorphic adenoma
• Poorly cohesive epithelial-like cells associated
  with fibromyxoid stroma.
• Warthins tumor
• Adenoid cystic carcinoma
• Acinic cell carcinoma

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• 69 year old male. FNA of neck mass
• Negative for malignancy
• Reactive lymphoid hyperplasia
• Metastatic squamous cell ca
• Metastatic melanoma
• Amebic abscess

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• 69 year old male. FNA of neck mass
• Negative for malignancy
• Reactive lymphoid hyperplasia
• Metastatic squamous cell ca
• Metastatic melanoma
• Amebic abscess

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18
BAL A. Candida B. Aspergillus C. PCP D.
Amebiasis E. Scedosporium
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• BAL
• A. Candida
• B. Aspergillus
• C. PCP
• D. Amebiasis
• Scedosporium
• If you picked this one all I can say is WOW!

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• 63 year old male. FNA of parotid
• Non diagnostic FNA
• Reactive lymph node in parotid gland
• Warthins tumor
• Acinic cell carcinoma
• Mucoepidermoid carcinoma

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• 63 year old male. FNA of parotid
• Non diagnostic FNA
• Reactive lymph node in parotid gland
• Warthins tumor
• Also called papillary cystadenoma lymphomatosum
  papilliferum. Lymphocytes and oncocytic cells.
• Acinic cell carcinoma
• Mucoepidermoid carcinoma

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