Endocrine System

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Endocrine System
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Endocrine System

• Endocrine glands are composed of cells that
  secrete
• Hormones
• amino acid derivatives
• peptides and proteins
• steroids

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• Hormones act by attaching to receptors of
  specific target cells

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• Function of endocrine system
• homeostasis
• growth and development

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Endocrine Glands

• Hypothalamus
• oxytocin production
• ADH production
• production and secretion of regulatory hormones
  for anterior pituitary

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• Pituitary (hypophysis)
• posterior pituitary
• oxytocin secretion
• ADH secretion

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• Pituitary (hypophysis)
• anterior pituitary
• Tropic hormones
• TSH
• ACTH
• Gonadotropins FSH, LH
• Prolactin
• Growth hormone

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• all anterior pituitary hormones are regulated by
  hypothalamic hormones
• regulation dependent upon hypophyseal portal
  system

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• Thyroid Gland

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• Thyroid Gland
• T4 and T3 released by thyroid follicles
• calcitonin released by C cells

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• Parathyroid glands

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• Parathyroid glands

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• Parathyroid glands
• PTH

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• Adrenal Gland

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• Adrenal Gland

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• Adrenal cortex
• mineralocorticoids
• glucocorticoids
• adrenal androgens
• Adrenal medulla
• E and NE

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• Endocrine pancreas
• Islets of Langerhans
• glucagon from alpha cells
• insulin from beta cells
• somatostatin from delta cells

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• Pineal gland
• melatonin
• Heart
• ANP
• Kidney
• renin
• EPO

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• Thymus Gland
• thymosin

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• Reproductive System
• Testes
• testosterone
• inhibin
• Ovaries
• estrogens
• progesterone

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Endocrine Disorders

• Acromegaly

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Endocrine Disorders, continued

• Acromegaly
• Gigantism

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Endocrine Disorders, continued

• Acromegaly
• Gigantism
• Pituitary Dwarfism

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Endocrine Disorders, continued

• Goiter

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Endocrine Disorders, continued

• Goiter

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Endocrine Disorders

• Graves disease

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Endocrine Disorders, continued

• Cretinism

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Endocrine Disorders, continued

• Cushings disease

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Endocrine Disorders, continued

• Cushings disease
• Addisons disease

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Endocrine Disorders, continued

• Type I diabetes
• Type II diabetes