Polycystic Ovarian Syndrome - PCOS

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Polycystic Ovaries
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The Most Common Endocrine Disorders
Disruption Of The Normal Regular Ovulation
Presented To The Clinicians With A Very Wide
Range Of Symptoms Signs
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Unknown
Weight Gain During Puberty
Environmental Influences
Familial Inheritance
Circulating Hormone Concentrations
Autosomal Dominant
Etiology - cause
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Clinical Presentation
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Lab Findings

• Increased androgens
• Increased LH
• Increased Fasting insulin
• Increased Prolactin
• Increased estradiol, estrone
• Decreased sex hormone binding globulin

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Differential Diagnosis
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USG Examination Findings

• Vaginal USG 100 Success
• Abdominal USG 30 Failure

The Characteristic Finding Is 10 Smaller Cysts
Measuring 2-8 mm In Diameter Surrounding An
Echo-Dense Sstroma
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Treatment Of PCO Focused On Symptoms

• Obesity To Weight reduction
• Metformin tablets To inhibit hepatic glucose and
  decrease insulin
• low-calorie diet for females with BMI gt30kg/m2
  truncal obesity.

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Treatment Of Menstrual Irregularity

• Low-dose combined oral contraceptive preparations
• Result in artificial non-ovulatory cycles and
  regular shedding of the endometrium

• Progesterone Medroxyprogesterone acetate or
  dydrogesterone for five days every one to three
  months

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• Infertility
• Ovulation can be induced by antiestrogenes,
  clomiphene citrate (5-100 mg) or tamoxifen 20-40
  mg on days two through six of natural or induced
  bleeding.
• In resistant cases, we can use parenteral
  gonadotrophin therapy with very careful
  continuous monitoring of the ovaries, or we can
  use laparoscopic diathermy.
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• Hyperandrogenism and hirsutism
• Treatment options include medical and cosmetic
  therapies.
• To stop further progression of hirsutism and
  decrease the hair growth rate, Will take at least
  six to nine months before any benefit is
  perceived.
• Physical treatment waxing, bleaching,
  electrolysis, and laser therapy,

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Surgical Treatment
Laparoscopic Diathermy
Wedge Resection
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The Late Squeals Of PCO
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