Manufacturing of Anti-Malaria Drug, Artemisinin, in Sub-Sahara Africa: (Nigeria).

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Manufacturing of Anti-Malaria Drug, Artemisinin,
in Sub-Sahara Africa (Nigeria).

• A Business Proposal and Plan

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The Problem - Malaria

• Today approximately 40-percent of the Worlds
  population is at risk of Malaria. Malaria causes
  more than 300 million acute illnesses, (compare
  to 40 million with AIDS).
• 90-percent of deaths due to Malaria occur in
  Sub-Sahara Africa, and mostly young children.
• Malaria kills an average of 2,000 African
  children a day. Pregnant women and their unborn
  children are particularly vulnerable to Malaria,
  which is a major cause of prenatal mortality, low
  

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A Temporary Solution

• Several major initiatives are planning to fund
  the manufacture of insecticide treated nets at
  10/net
• Nets last for a maximum of 5 years
• The solution is temporary

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The Need for Change

• Artemisinin, is one of the most effective drugs
  for treating Malaria today.
• Several studies have shown that Artemisinin is
  97-percent effective in treating multi-drug
  resistant Falciparum malaria infections, with no
  side effects and shorter duration of recovery.
• The old Malaria drugs are no longer effective.
• Nets alone will not eradicate malaria.

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Arteminsnine from Artemisin Annua
The main ingredient in Artemisinin-based
combination therapies, (ACTs)
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The Opportunity

• ACT medications are produced in Europe and
  imported to African Countries at about 9 per
  dose. A study conducted by Tanzanias National
  Institute for Medical Research showed that if
  produced locally in Africa, it could be sold for
  an affordable 2 per dose in all African
  Countries.

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Proposal

• This Business Proposal is to setup a state of art
  Pharmaceutical Manufacturing Company, to be
  called Pharmafric Drug Company in Africa
  (Nigeria).

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Purpose

• The purpose of this company shall be
• To manufacture Artemisinin for the treatment of
  Malaria for Africans.
• To locally farm, harvest, extract, purify and
  manufacture Artemisinin from its plant or other
  sources.
• To build a permanent infrastructure networks to
  deliver its products services throughout the
  whole Africa.
• To research into preventive measures, such as
  indoor residence spraying, mosquito nets and
  education of the public.
• To make itself an expert in the Prevention,
  Treatments and Eradication of Malaria in Africa.

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The Market

• PharmAfric would be a major supplier to all
  ECOWAS countries. ECOWAS is a group of 16-members
  West African countries with Trade and Economic
  Agreements with no boundary. This is a huge cash
  paying market.

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The Cost

• The total projected cost is about 15 millions.
• This estimated cost includes
• the Plant Machinery,
• farming of the plant, (Artemisia annua),
• starting up cost,
• payroll/operating cost for 2-years.

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Success Indicators

• The Labor market is plentiful, cheap and
  educated.
• The plant could be farmed locally, and hence
  there is nothing to import after the initial
  investment.
• Parametric is seeking a Grant, Donation or Loan
• The required Plant Machinery would have to be
  imported from United States or Europe. Artemisia
  annua would be grown

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Solar Power

• Needed for operation of farms, manufacturing
  plants and offices
• Major business opportunity given recent solar
  power improvements and innovations

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Management

• The management team will be led by Mr. Edward
  Olusegun Ayanbiola. Mr. Ayanbiola is a 55-years
  old Nigerian citizen, who has lived in United
  States for over 31-years. Mr. Ayanbiola has
  agreed to return back to Africa permanently to
  begin and direct this project. The estimated
  starting date is July 2008.
• Mr. Ayanbiola is a Pharmacist by profession. He
  obtained his Pharmacy Degree from Howard
  University, Washington DC in 1980. He has worked
  in different capacities as a Pharmacist/Pharmacy
  Manager in Washington DC metropolitan area,
  including owning managing his own Professional
  Drugstore for several years.

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Pharmafric Drug Company 9900 Greenbelt Road,
Suite E-258, Lanham, MD 20706. USA Tel (301)
552-4948. Fax [phone]. www.pharmafric.com