DNA

1
DNA - Code for Life
(1953)
(1962)
1920-1958
Died from ovarian cancer
2
Watson-Crick Complementarity
Conclusion DNA strands are complementary (1953).
of each base
Base ratios
DNA source
Human Sheep Turtle Sea urchin Wheat E. coli
Purines/ Pyrimidines
Purines
Pyrimidines
3
Watson-Crick Complementarity
A binds to T C binds to G
AATGCTTAGTC TTACGAATCAG
AATGCGTAGTC TTACGAATCAG
Perfect match
One base mismatch
4
DNA - (deoxyribonucleic acid) - THE Double Helix
Source Alberts et al
5
DNA Structure
control region
telomere
centromere
gene - coding region

• Control regions - DNA areas usually adjacent
  to genes.
• Determine when expressed and to what extend.
• Junk DNA - Unknown function.

6
A T C G
DNA Structure
Sugars
adenine
guanine
Bases
uracil
thymine
cytosine
7
The Nucleic Acid Sugars
Index Carbon Green, Oxygen Red, Hydrogen
Grey.
http//cbms.st-and.ac.uk/academics/ryan/Teaching/m
edsci/Medsci1.htm