Endocrine Development Slide Show

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Endocrine Glands
Hypothalamus Anterior Posterior
Pituitary Thyroid Parathyroid Ultimobranchial
Bodies (Parafollicular C-cells) Pancreas Adrenal
Medulla Adrenal Cortex Gonads
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Development of the Adrenal Cortex
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Steroid Hormone Biosynthetic Pathways
Gonads
Gonads
Adrenal
Adrenal
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Development of the Adrenal Cortex
SF-1 KO Mice Normal survival in utero Lack of
adrenal glands Lack of gonads Severe deficiency
in corticosterone Female internal genitalia in
both males and females Postnatal mortality
(on day 8)
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Adrenal Medulla Embryology
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Adrenal Medulla Embryology
Chromaffin Cells
Neural Crest Cells
Sympathetic Neurons
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Adrenal Medulla Embryology
Neural Crest Cells
Signal from mesoderm ?
Cortisol
Sympathoadrenal Cells
Chomaffin cells
Cortisol
FGF
FGF
NGF
Sympathetic Neurons
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Epinephrine Biosynthesis
Cortisol
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Pituitary The Master Gland
Hypothalamus
Pars Tuberalis
Pars Distalis
Pars Nervosa
Pars Intermedia
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Development of the Anterior Pituitary
Infundibular Process
Infundibular Process
Neural Ectoderm
Oral Ectoderm
Rathkes Pouch
Rathkes Pouch
Oral Cavity
Pars Nervosa
Pars Distalis
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Development of the Anterior Pituitary
Infundibular Process
Hypothalamus
Infundibular Process
Oral Ectoderm
Rathkes Pouch
Rathkes Pouch
LH Prl FSH GH TSH ACTH
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Development of the Thyroid
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Development of the Thyroid
Pouch I
Pouch II
Pouch III
Thyroid
Pouch IV
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Development of the Thyroid
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The Role of Thyroid Hormone in Development
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The Role of Thyroid Hormone in Development
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Development of the Parathyroids
Inferior Parathyroid (III)
Superior Parathyroid (IV)
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Development of Liver, Gall Bladder and Pancreas
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Development of the Pancreas
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Exocrine and Endocrine Tissue
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Pancreatic Islets of Langerhans
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Hyperinsulinemia in Fetus Causes Macrosomia
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Long Term Effects of Fetal Hyperinsulinemia