Neuro Brain Lab

1
Neuro Brain Lab

• Read lab manual and bring to lab.
• Bring a lab coat, gloves will be furnished.
• Pregnant students only allowed in lab with
  doctors permission.
• Lab will be in UCOM 6128
• Lab hours will be Monday-Friday 8-5,
  additional time may be arranged and announced to
  all students.
• No materials or atlases may be removed from
  the lab.
• Gloves must be discarded in red biohazard bags.

2
Structure of the Human Nervous System

• Selections from Chapter 7
• I. Overview VI. Ventricles
• II. Meninges VII. Brainstem
• III. CSF VIII. Diencephalon
• IV. Spinal Cord IX. Cerebral Cortex
• V. Brain Embryology X. Basal Ganglia

3
Introduction

• Review structures in anatomy text, and see Human
  Brain Atlas (lecture photos from website atlas)
• http//indy.radiology.uiowa.edu/Providers/Textbook
  s/BrainAnatomy/BrainAnatomy.html
• Also neuroscience text, chapter 7 (lecture
  diagrams from text figures)

4
I. Overview

• A. PNS
• 1. Nerves
• a. spinal
• b. cranial
• 2. Ganglia
• a. DRG
• b. autonomic ganglia
• c. cranial nerve ganglia

5
I. Overview

• B. CNS
• 1. Spinal cord
• 2. Brainstem medulla, pons, mesencephalon
• 3. Cerebellum
• 4. Diencephalon thalamus, hypothalamus
• 4. Cerebrum cerebral cortex, basal ganglia
• 5. Blood Supply

6
II. Meninges

• A. Dura mater
• 1. Spinal cord
• a. epidural space
• 2. Brain
• a. dural sinuses
• B. Arachnoid
• 1. Subarachnoid space
• 2. CSF
• C. Pia mater
• 1. BBB

From Brain Atlas website
7
III. CSF

• A. Formation
• 1. Choroid plexuses
• B. Flow
• 1. Ventricles
• 2. Subarachnoid spaces
• 3. Cisterns
• C. drainage
• 1. Arachnoid villi

Fig from anatomy text
8
IV. Spinal Cord

• A. Gross Anatomy
• 1. Anterior median fissure
• 2. Dorsal medial sulcus
• 3. Dorsal roots
• a. DRG
• 4. Ventral roots

From Brain Atlas website
9
IV. SpinalCord

• B. Cross sectional anatomy
• 1. Funiculi
• a. posterior, lateral, anterior
• 2. Dorsal horn
• 3. Ventral horn
• 4. Intermediate grey
• 5. Central canal

Fig from anatomy text
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V. Brain Embryology

• A. Neural Tube (7.8)
• 1. Neural plate
• 2. Neural groove

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V. Brain Embryology

• B. Primary Brain Vesicles 7.9
• 1. Prosencephalon
• 2. Mesencephalon
• 3. Rhombencephalon

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V. Brain Embryology

• C. Secondary Brain Vesicles 7.10
• 1. Telencephalon
• 2. Diencephalon
• 3. Mesencephalon
• 4. Metencephalon
• 5. Myelencephalon

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V. Brain Embryology

• D. Adult Brain Regions 7.21
• 1. Cerebrum
• 2. Thalamus hypothalamus
• 3. Midbrain
• 4. Pons cerebellum
• 5. Medulla

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VI. Ventricles

• A. Lateral ventricles 7.23
• 1. Anterior horn
• 2. Body
• 3. Posterior horn
• 4. Inferior horn

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VI. Ventricles

• B. Third ventricle 7.23
• 1. Interventricular foramen
• 2. Cerebral aqueduct
• C. Cerebral aqueduct

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VI. Ventricles

• D. Fourth ventricle 7.23
• 1. Foramen of Lushka
• 2. Foramen of Magendie
• E. Central canal

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VII. Brainstem

• A. Medulla
• 1. Pyramidal decussation
• 2. Cr. Ns. 8-12

From Brain Atlas website
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VII. Brainstem

• B. Pons
• 1. 4th ventricle
• 2. Basis pontis
• a. corticopontine fibers
• b. middle cerebellar peduncle
• 3. Cr. Ns. 5-8

From Brain Atlas website
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VII. Brainstem

• C. Midbrain
• 1. Cerebral aqueduct
• 2. Tectum
• a. superior colliculi
• b. inferior colliculi

From Brain Atlas website
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VII. Brainstem

• C. Midbrain
• 3. Tegmentum
• a. substantia nigra
• 4. Cerebral peduncles

From Brain Atlas website
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VIII. Diencephalon

• A. Third ventricle
• B. Thalamus
• C. Hypothalamus
• D. Pineal gland

From Brain Atlas website
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IX. Cerebral Cortex

• A. Landmarks
• 1. longitudinal
• fissure
• 2. gyri sulci
• 3. lateral fissure
• 4. central sulcus
• 5. parieto-
• occipital sulcus
• 6. poles frontal, temporal, occipital

From Brain Atlas website
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IX. Cerebral Cortex

• B. Lobes
• 1. frontal
• 2. parietal
• 3. occipital
• 4. temporal
• 5. insula

From Brain Atlas website
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X. Basal Ganglia

• A. Coronal Section
• 1. Caudate nucleus
• 2. Putamen
• 3. Globus pallidus

From Brain Atlas website
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X. Basal Ganglia

• B. Horizontal Section
• 1. Caudate nucleus
• 2. Putamen
• 3. Globus pallidus

From Brain Atlas website
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Lab Organization

• Required Lab Manual (Read before lab), Lab coats
• Furnished gloves, pointers
• Not allowed food drink
• Teams reader, pointer, kibitzer
• Times M-F 8-5
• Location UCOM 6128
• Specimens Handle with care and respect