Buy Arginine Cardio

1
Arginine Cardio Evidence-based reduction of
blood pressure (1)
L-Arginine is the precursor of Nitric
Oxide L-Citrulline potentiates the
bioavailability of L-arginine Arginine Cardio is
the L-Arginine supplement that has the highest
L-citrulline Content Nitric Oxide causes
vasodilation and thereby reduces blood pressure.
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Arginine Cardio Evidence-based reduction of
blood pressure (2)
L-Arginine is not being marketed by
pharmaceutical industry with a multi million
dollar budget for promotion. Clinical trials
with L-arginine to lower blood pressure have been
performed by independent academic research
institutions, with small research
budgets. Therefore, patient numbers in clinical
trials with L-arginine are comparatively
small. However, there is a recent meta-analysis
summarizing clinical trials with L-arginine.
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Arginine Cardio Evidence-based reduction of
blood pressure (3)
11 randomized, double-blind, placebo-controlled
trials involving 387 participants with oral
L-arginine intervention ranging from 4 to 24 g/d
Compared with placebo, L-arginine
intervention significantly lowered systolic
blood pressure by 5.39 mm Hg (95 CI -8.54 to
-2.25, P .001) and diastolic BP by 2.66 mm Hg
(95 CI -3.77 to -1.54, P .001).
Dong et al. American Heart Journal 2011
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Dong et al. American Heart Journal 2011
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Dong et al. American Heart Journal 2011
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Dong et al. American Heart Journal 2011
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Arginine Cardio Evidence-based reversal of
atherosclerosis (1)
Nitric Oxide has been known to protect from
atherosclerosis ever since the Nobel Prize for
Medicine was awarded for this finding in
1998. L-Arginine is the precursor of Nitric
Oxide. Animal experiments have unequivocally
proven in different models and in various
laboratories around the world that L-arginine can
reverse atheroslcerosis. Whilst no big,
multinational studies could be performed with
L-arginine due to lack of funding from public
sources, multiple studies have shown reversal
of endothelial dysfunction, the early clinical
sign of atherosclerosis, by L-arginine. We have
a collection of case reports that show reversal
of atherosclerotic plaque in humans during a few
months of L-arginine intake.
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Study A Prevention of Plaque Build-Up
Design
Cholesterol L-Arginine
Cholesterol
Control
0
weeks
8
Results
Böger et al., Atherosclerosis 1995 117 273 284
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Study B Stopping the Progression of Plaque
Build-Up
Cholesterol L-Arginine
Design
Cholesterol
Cholesterol
Cholesterol Lovastatin
Control
Control
0
weeks
10
16
4
Results
50
40
Dietary L-arginine completely suppressed the
aggravation of intimal plaque formation during
the second part of the study Lovastatin
treatment significantly reduced the progression
of plaque formation but did not completely block
it.
30
-92
Intimal plaque area (carotid artery)
20
10
0
0
weeks
16
4
Böger et al., Circulation 1997 96 1282-1290
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Study C Reversal of Pre-Existing Plaque
Design
Cholesterol
Cholesterol
Cholesterol L-Arginine
Cholesterol
0
weeks
18
23
10
Results
75
60
This is the first demonstration that
restoration of NO activity can induce
regression of preexisting intimal lesions and
provides evidence that L-arginine therapy may be
of potential clinical benefit
45
Intimal plaque area (carotid artery)
30
15
0
0
weeks
23
10
18
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Candipan et al., Arterioscler. Thromb. Vasc.
Biol. 1996 16 44-50
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