Term Project Proposal Presentation

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Term Project Proposal Presentation

• 2006. 06. 12

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Database Online Mendelian Inheritance in skin
with OMIM DB
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Introduction
Online Mendelian Inheritance in Man (OMIM) OMIM
is a continuously updated catalogue of human
genes and genetic disorders. OMIM focuses
primarily on inherited, or heritable, genetic
diseases. It is considered to be a phenotypic
companion to the human genome project. OMIM is
based upon the text Mendelian Inheritance in Man,
authored and edited by Dr. Victor A. McKusick and
a team of science writers and editors at Johns
Hopkins University and elsewhere. Mendelian
Inheritance in Man(MIM) is now in its 12th
edition. See McKusick, V.A. Mendelian
Inheritance in Man. 12th ed., Baltimore Johns
Hopkins University Press, 1998.
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Purpose
- Limitation of datas about skin genetic
disorders in OMIM - the updated data in other
databases is considerably insufficient.
OMIK(Online Mendlian Inheritance in
Korea) information is simple
and Page error ?????lt???? DBgt
late update
Korea Cytogenetic DB page
error - All of the database is not up to date
( old ) - Databases include overlapped
cytogenetic DB - contents of the databases are
insufficient for professional and accuracy

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Method
OMIM
Get id from html pages(/omimhtml) ( skin search
) Method python 2.4 Searched results with skin
2189
Raw data
Download the pages(/omimsubhtml) with id Method
python 2.4
html data
Extract the datas from downloaded pages Method
python 2.4
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Method
extracted data
insert datas (text file) to the data table Method
MS Access !! but except data if data is too
large to insert to the table
Data table
Make form for the table
Method MS Access
form
Coding to add search function with visual
basic Method MS Access (visual basic)
Skin DB
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Result
search
Title OMIM id
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Result
In the Searched data

If click the OMIMlink,
If click the Genelocus,
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Discussion
- Skin database can be used to search genetic
disorders in skin. - The information in this
database is easier to see and understand through
visualization datas and picture informations
than previous OMIM DB. - DB is not linked to
the web. - But this skin DB have limitations.
? Most part of the information in DB exist in
OMIM DB. ? Earning the pictures about genetic
disorder is difficult. ( shortage of
knowledge)