Platelet Rich Plasma Hair Loss Treatment

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PLATELET RICH PLASMA (PRP) Treatment
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INTRODUCTION

• Platelet Rich Plasma (PRP) is cutting edge
  therapy in the field of cosmetic enhancements.
• Although the procedure is relatively new ,PRP has
  been recognized as an effective treatment in
  sports injury, diabetic ulcer treatment, and
  orthopedics to name a few.
• Now patients who wish to use their own bodys
  regenerative power can do so without the concerns
  for infection, foreign material, or surgical
  interventions.

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PLATELET RICH PLASMA (PRP)

• Platelet-rich plasma (PRP) is blood plasma that
  has been enriched with platelets. As a
  concentrated source of autologous platelets, PRP
  contains several different growth factors and
  other cytokines that stimulate healing of bone
  and soft tissue.

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PLATELET RICH PLASMA

• What is PRP?
• Human blood is comprised primarily of red blood
  cells (RBC), as well as white blood cells (WBC),
  platelets, and plasma.
• By initiating the first step of coagulation,
  platelets are the key to the bodys ability to
  heal wounds.
• It is thought that by increasing the platelet
  count in a wounded area, the bodys healing to
  that area would be accelerated explaining the
  use of PRP (platelet rich plasma) in wound
  healing.
• Platelet rich plasma is concentrated blood plasma
  which contains approximately five times the
  number of platelets found in normal circulating
  blood. In addition, blood plasma contains the
  growth factors PDGF and VEGF and other bioactive
  proteins that aid in wound healing.

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PREPARATION

• There are, at present, two methods of PRP
  preparation approved by US FDA.3
• Both processes involve the collection of whole
  blood that is anticoagulated with citrate
  dextrose) before undergoing two stages of
  centrifugation designed to separate the PRP
  aliquot from platelet-poor plasma and red blood
  cells.
• 3 In humans, the typical baseline blood platelet
  count is approximately 200,000 per µL
  therapeutic PRP concentrates the platelets by
  roughly five-fold.67

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COMPOSITION OF BLOOD

• R.B.C- 93
• W.B.C- 1
• PLATELETS AND PLASMA-6
• _at_Platelet activation -------- Growth Factor
  release-------------accelerared tissue and wound
  healing.

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PREPARATION

• PRP can easily be seperated from blood , through
  a process of CENTRIFUGATION
• Using your enriched plasma permits the body to
  heal faster and more efficiently
• because your plasma (autologous) is used there is
  no danger of disease transmission or allergic
  reaction.

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BASIS PRP

• The basis of PRP lies in decreasing RBC count to
  5 since they are less useful in healing process
  while increasing platelet count to 94
• PRP or blood plasma is the source of concentrated
  platelet content present in the blood.

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USES OF PRP

• MEDICAL USES
• Acceleration of healing of tendon injuries
• osteoarthritis treatment
• jaw reconstruction
• cardiovascular medicine.
• The concentrated form of plasma has been shown
  to accelerate wound healing and tissue repair
  and, thus, could potentially benefit hair
  restoration procedures
• In hair transplantation, PRP can be injected into
  the recipient site area to theoretically
  stimulate the healing of the transplanted grafts
  and into the donor area to facilitate healing
  of the donor incision.
• Scar treatment

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PRP AND HAIR

• Growth factors in PRP when released promote
• Tissue repair
• Angiogenesis (capillary formation)
• Capillary production
• Normalisation of hair follicular unit
• PRP can reverse miniaturisation process of hair
  follicles
• Wake up dormant follicular stem cells

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RESULT AFTER 2 SITTINGS OF PRP
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PRP AND FUE

• Follicular unit transplantation outcomes may be
  increased by the correct application of PRP.
• Donor site pre-treatment with PRP ( purpose is to
  provide platelet cell therapy and
  platelet-derived growth factors, both of which
  are key elements in wound healing).
• Recipient site pre-treatment with PRP ( this
  seems to be an important factor affecting graft
  growth and survival rates).
• Optimal use of intra-operative PRP and
  platelet-derived growth factors, in and around
  the graft
• Graft emersion in PRP ( soaking the graft in
  the PRP gel)

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PRP AND FUE

• Following advantages are claimed by use of PRP
• to enhance donor site wound healing
• to decrease the incidence of infection
• to reduce donor scarring
• to increase donor scar tensile strength
• to enhance recipient site healing (which should
  increase growth)
• to be utilized as an effective treatment protocol
  in severe cases of wound dehiscence or infection.

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