Clinical Microbiology

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Clinical Microbiology

• Faculty TA
• Joanna Shisler Katherine Ayoade
• James Slauch
• Dixie Whitt

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Role of Clinical Microbiology in the M-2 year

• Build on basic concepts of medical microbiology
  presented in the M-1 year
• Assure that material presented is complimentary
  to that taught in FCP

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Mechanisms for accomplishing the role of Clinical
Microbiology

• Provide current information about important
  microbial pathogens
• Describe mechanisms by which these pathogens
  cause disease
• Encourage understanding of basic molecular
  pathogenic mechanisms

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Lectures for first portion of Clinical
Microbiology

• Basic virology (virus-host interaction)
• Vaccines (design, types, delivery, mechanisms of
  immune response)
• Clinical molecular microbiology (how different
  types of molecular techniques are used in
  diagnosis)
• Current topics (antibiotic resistance, emerging
  diseases, bioterrorism)

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Material in second part of Clinical Microbiology
(organ system based)

• Urinary tract infections
• Sexually transmitted infections
• Respiratory tract infections
• Gastrointestinal tract infections
• CNS infections
• Infections of skin, soft tissues, muscle, and
  associated systems
• Vector-borne infections and zoonoses
• Infections in immunocompromised patients

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Active learning activities

• Question and answer sessions associated with
  didactic lectures
• Students provided with reading material and list
  of questions
• Students expected to discuss questions in class
• Small group exercises (POPS)
• Students provided with case materials
• Work together in class to determine diagnosis

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Goals and objectives

• Know characteristics of pathogens in each organ
  system
• Know major host defenses of each organ system
• Appreciate role of host response in infectious
  disease
• Understand molecular bases for vaccine design,
  treatment strategies, and clinical diagnostic
  testing
• Understand necessity and timing of vaccination
  and how vaccines work
• Know clinical importance of antibiotic resistance
• Be aware of emerging and reemerging infectious
  diseases and associated problems
• Know pathological manifestations of infectious
  disease, how detected in lab and how controlled
  in hospital environment
• Know major agents likely to be used by
  bioterrorists