What are statins? | Online Course | Udemy

1
What are Statins?

• HMG-CoA reductase inhibitors (statins)
  selectively block an enzyme named HMG-CoA
  reductase which is contributed in the composition
  of mevalonate.
• cholesterol as well LDL-cholesterol synthesis is
  declined.
• Statins also elevate LDL receptors number on
  liver cells.
• Nearly most of the statins' effects happen in the
  liver.

2
What are Statins?

• Apolipoprotein B, cholesterol, and
  LDL-cholesterol.
• Statins may be utilized in the therapy of
  hyperlipidemia.

3
Drugs contain Atorvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Trovan 10, 20, 40, 80 Pharmacare Tablet
4
Drugs contain Atorvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Lipidex 10, 20, 40 Birzeit Tablet
5
Drugs contain Atorvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Liponil 10, 20 Jepharm Tablet
6
Drugs contain Atorvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Lolip 10, 20, 40, 80 Beit Jala Tablet
7
Drugs contain Atorvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Atorvastatin Teva 10, 20, 40, 80 Teva Tablet
8
Drugs contain Atorvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Lipitor 10, 20 Pfizer Tablet
9
Drug Information

• Therapeutic Index hypolipidemic agents
• Drug and food Interaction Grapefruit it
  increases the amount of drug in bloodstream.

10
Drug Information
Drug Drug Interaction digoxin, erythromycin,
clarithromycin, itraconazole. Side Effects
Muscle weakness, headache, thinness,
dizziness. Pregnancy Category D
11
Drugs contain Simvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Simvastatin 10, 20, 40, 80 Teva Tablet
12
Drugs contain Simvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Simovil 10, 20, 40, 80 MSD Tablet
13
Drugs contain Simvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Simvaxon 10, 20, 40, 80 Dexxon Tablet
14
Drugs contain Simvastatin
Trade Name mg in each tablet Manufacturer Dosage Form
Simvacor 10, 20, 40, 80 Unipharm Tablet
15
Drug Information

• Therapeutic Index hypolipidemic agents
• Side Effects Pain and digestive disorders
• Pregnancy Category X