Instgra and Tafero EM 12 Months Tablets Uses, MRP Price india.

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INSTGRA AND TAFERO EM 12 MONTHS
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DESCRIPTION

• Instgra Tafero EM tablet are used for treatment
  involved in HIV-1 infections.
• Instgra tablet are containing Dolutegravir as an
  active component whereas Tafero EM tablets are
  containing Tenofovir Alafenamide Emtricitabine
  as active ingredients.
• Instgra is pharmacologically classified as an
  integrase inhibitor.
• Tafero EM is pharmacologically classified as
  nucleoside reverse transcriptase inhibitor.

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DESCRIPTION

• This Instgra Tafero EM combination is approved by
  FDA, which may provide better activity against
  HIV-1 infections.
• Instgra Tafero EM should not have capability of
  curing the HIV infection, but it can able to
  reduce the development of HIV-1 further to AIDS.
• This is a fixed dose combination of one Integrase
  inhibitor with two nucleoside reverse
  transcriptase inhibitors.

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PROPERTIES

• Brand name Instgra Tafero EM 12 months tablets
• Active components Dolutegravir Tenofovir
  Alafenamide Emtricitabine
• Strength 50mg 25mg 200mg respectively
• Pack 30 tablets in a container of both products
• Mfg Instgra Emcure Tafero EM - Hetero
• Category Anti-retroviral drugs

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Mechanism of Instgra Tafero EM

• Instgra- Dolutegravir is a competitive to virus
  associated to HIV infection.
• Dolutegravir is an Integrase strand transferase
  inhibitor, which is active against HIV type 1
  infection. Dolutegravir binds to the active site
  of integrase enzyme, HIV enzyme that helps to
  transmit viral genetic material into human
  chromosomes.
• This binding inhibition prevents integrase
  binding to retro virus DNA and causes blockade of
  strand transfer step which is required for cell
  proliferation process.

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Mechanism of Instgra Tafero EM

• Instgra helps to prevent the HIV type 1 cell
  production.
• TAF is manufactured as prodrug, which is
  conversed into active form inside the body known
  as tenofovir. TAF containing cell permeability
  activities, through this effect it get penetrate
  into the infected cells and changed over as
  tenofovir.
• Inside the cells, tenofovir is phosphorylated
  into tenofovir diphosphate by hydrolysis.

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Mechanism of Instgra Tafero EM

• Tenofovir diphosphate shown anti-retroviral
  activity by intercedes into viral DNA and causes
  inhibition of chain formation leads to stopping
  the viral production.
• Emtricitabine into Emtricitabine 5 triphosphate,
  this conversion occurs inside the body and causes
  chain eliminator effect by struggling with
  deoxycytidine 5triphosphate.

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Instgra Tafero EM caused side effects

• Instgra associated side effects
• Hypersensitivity reactions
• Liver toxicity
• Immune reconstitution syndrome
• Insomnia
• Depression
• Abnormal dreams
• Dizziness
• Headache

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• Diarrhea
• Nausea
• Rash
• Fatigue
• Vertigo
• Elevation of
• AST, ALT
• Bilirubin

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• Creatine kinase
• Blood glucose
• Lipase
• Post marketing effects
• Acute liver damage, liver toxicity
• Arthralgia
• Myalgia
• Anxiety

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Tafero EM associated side effects

• Aggravation of hepatitis B
• Immune reconstitution syndrome
• Outbreak or severity of renal impairment
• Lactic acidosis or hepatic steatosis
• Loss of bone mineral density
• Laboratory abnormality
• Virological response alteration

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Pregnancy and lactation

• Pregnancy category of Tafero EM is B Instgra is
  B
• Instgra Tafero EM uses in pregnancy condition as
  cautiously. Counsel the patients about the risk
  benefits before starting the treatment with
  Instgra Tafero EM.
• Breast feeding should not be allowed.

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• Storage and handling
• Instgra container should be stores at 25oC
  Tafero EM should be stored below 30oC.
• Protect from light
• Keep away from moisture heat
• Missed dose
• In case of missed dose, patient must be consult
  with physician and follow the regular dosing
  schedule.

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CONACT US

• PHONE NO91 9940472902
• EMAILmillionhealthpharmaceuticals_at_gmail.com
• WEBSITEhttps//pillsbag.com/products/instgra-and-
  tafero-em-12-months