Title: NEUROMYELITIS OPTICS THERAPY MARKET ANALYSIS(2020-2027)
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2NEUROMYELITIS OPTICS THERAPY MARKET ANALYSIS
(2020-2027)
- Neuromyelitis Optics Therapy Market, by Drug
Class (Corticosteroids, Immunosuppressive Agents
(Azathioprine, Mycophenolate Mofetil, Rituximab,
Eculizumab), and Others), by Distribution Channel
(Online Retail Pharmacies and Offline Retail
Pharmacies), and by Region (North America, Latin
America, Europe, Middle East, Asia Pacific, and
Africa)
3- Neuromyelitis optica is an autoimmune disorder,
in which white blood cells and antibodies attack
optic nerve as well as spinal cord. Furthermore,
damage of the optics nerves results in pain and
loss of vision, while damage of spinal cord
results in paralysis of legs or arms, loss of
sensation in legs and arms, and problem in the
function of bladder bowel. - Moreover, there is no cure for neuromyelitis
optica disorder, but there are therapies to treat
acute attack of relapses, and to reduce symptoms.
Neuromyelitis optica attacks and Neuromyelitis
optica relapses are often treated with plasma
exchange and corticosteroids. Moreover, initial
symptoms of neuromyelitis optica such as vision
loss and paralysis can be improve with high doses
of intravenous corticosteroids. On the other
hand, plasma exchange can be used as alternative,
if the patient do not respond to intravenous
corticosteroids. For long term suppression of
disease, immunosuppressive agents such as
azathioprine, mycophenolate mofetil, and
rituximab are used to prevent the attack.
Sometimes, azathioprine and mycophenolate mofetil
are used with the low doses of corticosteroid to
prevent the attack.
4Global Neuromyelitis Optica Therapy Market
Drivers
- The global neuromyelitis optica therapy market is
expected to witness significant growth over the
forecast period, owing to increasing
collaborations to launch new drugs for the
treatment of neuromyelitis optica spectrum
disorder. For instance, in May 2019, in China,
Viela Bio, Inc. entered into strategic
collaboration with Hansoh Pharmaceutical Group
Company Limited (Hansoh Pharma) to develop as
well as commercialize inebilizumab drug for the
treatment of autoimmune disorder such as
neuromyelitis optica spectrum disorder. From the
same source, in May 2019, Viela Bio had presented
positive result from the pivotal study of
inebilizumab in patient. Moreover, currently
inebilizumab drug is not approved by the U.S Food
and Drug Administartion (FDA) for sale in China
and U.S
5- Furthermore, rising incidence of neuromyelitis
optica disorder among people is expected to
propel global neuromyelitis optica therapy market
growth. For instance, according to the U.S
National Library of Medicine (NHS) 2019 report,
prevalence of neuromyelitis optica spectrum
disorders (NMOSD) is commonly observed in nations
with a predominately non-Caucasian population and
estimated to be high as 10 per 100,000
individuals.
6- Global Neuromyelitis Optica Therapy Market
Restraints -
- However, high cost of drug such as eculizumab for
the treatment of neuromyelitis optica spectrum
disorder (NMOSD) yet remains one of the major
restraints for global neuromyelitis Optica
therapy market growth. For instance, cost of
eculizumab is US 500,000 per patient per year,
which is one of the most expensive therapies in
the world for the treatment of neuromyelitis
optica spectrum disorder (NMOSD). - Moreover, side effects associated with the
eculizumab such as upper respiratory tract
infection, back pain, anemia, nasal congestion,
urinary tract infection for the treatment of
neuromyelitis optica spectrum disorder (NMOSD) is
another factor that is expected to hamper the
global neuromyelitis optica therapy market
growth.
7- Global Neuromyelitis Optica Therapy Market
Regional Analysis - .Among regions, North America is expected to
account for highest market share in the global
neuromyelitis optica therapy market, owing to
factors such as increasing approval of drugs for
the treatment of neuromyelitis optica spectrum
disorder (NMOSD) by company. For instance, in
January 2019, Alexion Pharmaceuticals, Inc.
received approval by the U.S Food and Drug
Administartion (FDA) for eculizumab
(Soliris) drug for the treatment of neuromyelitis
optica spectrum disorder (NMOSD) in adult
patients. Furthermore, from the same source,
eculizumab (soliris) has reduced the need of
corticosteroid and plasma exchange to prevent
acute attack in patients, who are suffering from
neuromyelitis optica spectrum disorder (NMOSD).
8- Asia Pacific is expected to exhibit highest CAGR
in the global neuromyelitis optica therapy market
in the forecast period due to increasing approval
of drug for the treatment of neuromyelitis optica
spectrum disorder (NMOSD) by company. For
instance, in November 2019, Alexion
Pharmaceuticals, Inc. received approval from
Japans Ministry of Health, Labour and Welfare
(MHLW) for its Soliris (eculizumab) drug for the
treatment of neuromyelitis optica spectrum
disorder (NMOSD) to prevent relapse in patient.
9- Furthermore, increasing number of clinical trials
of drug for the treatment of neuromyelitis optica
spectrum disorder (NMOSD) by company is another
factor that is expected to drive the global
neuromyelitis optica therapy market growth. For
instance, in September 2019, Chugai
Pharmaceutical Co., Ltd. announced positive
results of its phase 3 clinical study of
satralizumab drug, for the treatment of
neuromyelitis optica spectrum disorder (NMOSD).
From the same source, in 2019, Satralizumab had
shown safety profile during the clinical trial
and is first investigational drug that had
demonstrated benefits both as a monotherapy and
add-on therapy to baseline treatment in two
different clinical trials. Furthermore, from the
same source, in 2019, Chugai Pharmaceutical Co.,
Ltd also announced that they are going to
collaborate with F. Hoffmann-La Roche AG Company.
The main objective of this collaboration with
Hoffmann-La Roche AG company is to file global
regulatory application and bring Satralizumab as
a potential new treatment to patients as soon as
possible.
10- Furthermore, in October 2019, European Medicines
Agency (EMA) and U.S. FDA accepted the marketing
authorization of Satralizumab drug for the
treatment of neuromyelitis optica spectrum
disorder in adults and adolescent patients, which
was announced by Chugai Pharmaceutical Co., Ltd.
11- Global Neuromyelitis Optica Therapy Market Key
Players - Key players operating in the global neuromyelitis
optica therapy market include Alexion
Pharmaceuticals Inc., Chugai Pharmaceutical Co.,
Ltd., Viela Bio, Inc, Hansoh Pharmaceutical Group
Company Limited, AstraZeneca plc, F. Hoffmann-La
Roche AG, Zydus Pharmaceuticals (USA) Inc., Alkem
Laboratories, Hikma Pharmaceuticals USA Inc., and
Sandoz Inc.
12- Market Taxonomy
- On the basis of drug class, the global
neuromyelitis optica therapy market is segmented
into -
- Corticosteroids
- Immunosuppressive Agents
- Azathioprine
- Mycophenolate Mofetil
- Rituximab
- Eculizumab
- Others
13- On the basis of distribution channel, the global
neuromyelitis optica therapy market is segmented
into - Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
- On the basis of region, the global neuromyelitis
optica therapy s market is segmented into - North America
- Latin America
- Europe
- Middle East
- Asia Pacific
- Africa
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