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Brand RIBOCICLIB Generic KISQALI

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• KISQALI RIBOCICLIB tablets
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• What is RIBOCICLIB?
• Ribociclib is used to treat hormone-related
  breast cancer in women. Ribociclib is used only
  if your cancer tests negative for a protein
  called human epidermal growth factor receptor 2
  (HER2). HER2 protein can speed the growth of
  cancer cells.
• Ribociclib is used when the cancer has progressed
  or has spread to other parts of the body after
  other treatments.
• Ribociclib is given in combination with another
  cancer medicine such as letrozole (Femara) or
  fulvestrant (Faslodex).
• Ribociclib may also be used for purposes not
  listed in this medication guide.
• Warnings
• Ribociclib can cause serious side effects on your
  heart, liver, or lungs. Call your doctor at once
  if you have chest pain, fast or pounding
  heartbeats, trouble breathing, cough (with or
  without mucus), sudden dizziness, right-sided
  upper stomach pain, loss of appetite, unusual
  bleeding or bruising, dark urine, or yellowing of
  your skin or eyes.

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• How should I take RIBOCICLIB?
• Follow all directions on your prescription label
  and read all medication guides or instruction
  sheets. Use the medicine exactly as directed.
• Ribociclib is given in a 28-day treatment cycle.
  You will take the medicine for the first 21 days
  of each cycle, followed by 7 days off. Your
  doctor will determine how long to treat you with
  ribociclib.
• Swallow the tablet whole and do not crush, chew,
  or break it.
• Take the medicine at the same time each morning,
  with or without food.
• If you vomit after taking the medicine, wait
  until the next day to take your next dose.
• Do not use a broken or damaged pill.
• You may need frequent medical tests to be sure
  ribociclib is not causing harmful effects. Your
  cancer treatments may be delayed based on the
  results.
• Store ribociclib in the original container at
  room temperature, away from moisture and heat.

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• What happens if I miss a dose?
• Skip the missed dose. Take your next dose at the
  regular time and stay on your once-daily
  schedule. Do not use 2 doses in one day.
• What happens if I overdose?
• Seek emergency medical attention or call the
  Poison Help line at 1-800-222-1222.
• What should I avoid while taking RIBOCICLIB?
• Grapefruit may interact with ribociclib and lead
  to unwanted side effects. Avoid the use of
  grapefruit products.
• Avoid taking an herbal supplement containing St.
  John's wort at the same time you are taking
  ribociclib.

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• RIBOCICLIB
• Get emergency medical help if you have signs of
  an allergic reaction (hives, difficult breathing,
  swelling in your face or throat) or a severe skin
  reaction (fever, sore throat, burning eyes, skin
  pain, red or purple skin rash with blistering and
  peeling).
• Seek medical treatment if you have a serious drug
  reaction that can affect many parts of your body.
  Symptoms may include skin rash, fever, swollen
  glands, muscle aches, severe weakness, unusual
  bruising, or yellowing of your skin or eyes.
• Call your doctor at once if you have
• fast or pounding heartbeats, fluttering in your
  chest, shortness of breath, and sudden dizziness
  (like you might pass out)
• low white blood cell counts--fever, mouth sores,
  skin sores, sore throat, cough, trouble
  breathing
• signs of inflammation in the lungs--new or
  worsening cough, painful or difficult breathing,
  wheezing, feeling short of breath even while
  resting or
• liver problems--loss of appetite, upper stomach
  pain, tiredness, easy bruising or bleeding, dark
  urine, jaundice (yellowing of the skin or eyes).

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