What is ICSI Treatment and Who is it For?

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11 Questions On ICSI Treatment m DR SHIVANI,
PREGNANCY
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ICSI Treatment is one of the most popular
techniques for fertility treatment. ICSI
Treatment is done best in SCIIVF by doctors with
decades of experience. What is ICSI
Treatment? It is a test-tube fertilization
procedure in which a sperm is injected directly
into an egg to achieve fertilization. ICSI is
done for male infertility. ICSI Treatment
What is the difference between ICSI and
IVF? Intracytoplasmic sperm injection (ICSI)
differs from conventional in-vitro fertilization
(IVF) in that the embryologists select a single
sperm to be injected directly into an egg,
instead of fertilization taking place in a dish
where many sperm are placed near an egg. Who
should be treated with ICSI? ICSI is mainly done
for male infertility. You are recommended ICSI
if- You have a very low sperm count. Other
problems with the sperm have been identified,
such as poor morphology (abnormal shape ) or poor
motility (not moving normally) You need sperm to
be collected surgically from the testicles or
epididymis for example because you have had a
vasectomy, you do not ejaculate sperm because you
have extremely low sperm production. During
previous attempts at IVF, there was the failure
of fertilization or an unexpectedly low
fertilization rate. You are using embryo
testing. You are using frozen sperm in your
treatment which is not of optimum quality. What
are the common reasons used for performing ICSI?
ICSI is the latest of several micro-fertilization
techniques that have been utilized predominately
to overcome severe male subfertility, giving
fertilization and term pregnancy rates similar to
conventional in-vitro fertilization. Absolute
indication include Use of epididymal or
testicular sperm samples. High titers of
anti-sperm antibodies.
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When only acrosomeless or immotile spermatozoa
are avoidable. Fertilization of oocytes prior to
preimplantation genetic diagnosis. For
women-Women are given fertility drugs to
stimulate ovaries and produce more eggs as for
IVF and progress is monitored through vaginal
ultrasound scans and possibly blood tests For
men-The, embryologists will examine the sperm
under a microscope and decide whether ICSI could
increase the chances of fathering a baby. The
eggs are then collecte4d using the same procedure
as IVF and each egg is injected with a single
from the partner or donor. The rest of the
procedure is the same as IVF. ICSI
Treatment- Pre-treatment- Before your treatment
starts, you will need to example various consent
forms and may need to undergo various blood tests
to screen for HIV, hepatitis B and C, and HTLV
virus. How is ICSI treatment carried out? The
next step depends on whether you are able to
provide sperm without a medical procedure If
you can, you produce a fresh sperm sample on the
same day as your partners eggs are
collected. Sperm can be collected directly from
the epididymis using a type of fine syringe. This
is known as PESA. Sperm can also be retrieved
from the testicles, a process known as TESA. It
is also possible to remove tiny quantities of
testicular tissue from which sperm can be
extracted. This procedure is called TESE. If you
have stored sperm, it will be removed from frozen
storage, thawed, and prepared. A single is then
injected into each egg. Finally, if
fertilization does take place the embryo will be
cultured in the laboratory for up to six days and
then between one and three of the best quality
embryos will be transferred to the womb. What
are the advantages of ICSI treatment? ICSI is a
procedure that effectively eliminates male
infertility by introducing sperm cells directly
into an egg. ICSI is the perfect solution to the
main causes of male infertility like low sperm
count, poor motility, and poor sperm shape. ICSI
benefits extend beyond just acting as a treatment
for male infertility but also for anyone who is
paralyzed or has had an irreversible
vasectomy. It is an option for couples who have
tried and failed at standard IVF treatment.
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What are the
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disadvantages of ICSI treatment? ICSIS method of
directly introducing sperm into an egg defeats
the natural process of only a select few sperm
making it to and fertilizing an egg. This can be
a disadvantage because the selection process is a
natural way of making sure that the best sperm,
with the best genetic material, are the ones with
the best chance of fertilizing the egg. Removing
that selection process can lead to an increased
risk of developmental and health issues for ICSI
children as well as higher health risks of
miscarriage because of the poor genetic material
involved. Women 35-37 yr 42 Women 41-42 yr
20.4 One cycle of ICSI takes between four-six
weeks to complete. Embryo may be transferred
in two to three days after fertilization, or five
days after fertilization. Five days after
fertilization the embryo will be at the
blastocyst stage.
What is the cost of ICSI Treatment? It can cost
around RS 45000/- to Rs. 60000/-. What are the
fertilization and pregnancy success rate of ICSI
Treatment? ICSI often boosts in-vitro
fertilization (IVF) success rates for couples
dealing with male infertility. ICSI Treatment
success rates for live birth- Given below are
birth rates, grouped by mothers age, for couples
that underwent an embryo transfer and had a
diagnosis of male infertility. Women under 35
48.3 Women 35-37 yr 42 Women 38-40 yr
29.8 Women 41-42 yr 20.4 Over age 42 yr
7 One key to ICSIs success is that ICSI
improves the odds of fertilization. Approximately
50 to 80 of eggs are fertilized during the ICSI
procedure. How many days rest required after
ICSI Treatment? Embryo may be transferred in two
to three days after fertilization, or five days
after fertilization. Five days after
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fertilization the embryo will be at the
blastocyst stage. One cycle of ICSI takes
between four -six weeks to complete. For Further
Information on ICSI Treatment in Delhi you
contact Dr. Shivani Sachdev Gour at
011-41041131/9999664422, Email
info_at_sciivf.com OR you may provide your
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