Concussion: return-to-play guideline

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Concussion return-to-play guideline

• Thao M. Nguyen, MD
• PEM fellow
• Fellows Conference
• June 20, 2007

2
Case

• 17 yo male with LOC following a football tackle.
  He has retrograde amnesia to the days event,
  confusion, and initial weakness. This is his 2nd
  concussion. Brought to the ER by the family for
  evaluation
• Exam VSS alert and oriented x 4 follows command
  but slightly slow in response from his baseline
  nonfocal neurological exam.
• Head CT negative
• Final diagnosis closed head injury with LOC
• You plan to discharge pt home in familys care
  with head injury sheet. What further discharge
  instructions should you provide?

3
Objectives

• Definition epidemiology
• Review the symptoms complications of concussion
• Discuss the evolution of the return-to-play
  guidelines
• Acute and long-term management

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Definition

• Trauma-induced alteration in mental status that
  may or may not involve loss of consciousness.
• AAN 1997
• lt 10 of concussions result in LOC
• Confusion and amnesia are the hallmarks of
  concussion
• Type of mild traumatic brain injury (TBI) caused
  by an impact or jolt to the head.
• Pediatrics 2006
• a complex pathophysiologic process affecting the
  brain, induced by traumatic biomechanical
  forces.
• CISG 2001

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Epidemiology

• 21 malefemale
• most common head injury in sports
• gt300,000 sport-related mild-to-mod TBIs
• high school football alone
• 20 of players or 250,000 concussions/year
• 10 in college football players
• Other risky sports equestrian, boxing, ice
  hockey, wrestling, gymnastics, lacrosse, soccer
  and basketball
• 4-6x more likely to sustain a 2nd concussion
• Cantu. Br J Sports Med 1996

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Epidemiology

• Sports Rate of concussions/1000
  athlete-exposures
• Ice hockey 0.27
• Football 0.25
• Mens soccer 0.25
• Womens soccer 0.24
• Field hockey 0.20
• Wrestling 0.20
• Mens lacrosse 0.19
• Womens softball 0.11
• Kelly, Neurology 1997

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Observed symptoms

• Vacant stare
• Delayed verbal and motor responses
• Confusion and inability to focus attention
• Disorientation
• Slurred or incoherent speech
• Gross observable incoordination
• Emotions out of proportion to circumstances
• Memory deficits
• Any period of loss of consciousness AAN
  Practice Parameter, Neurology 1997

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Early symptoms minutes to hours

• Headache
• Dizziness or vertigo
• Lack of awareness of surroundings
• Nausea or vomiting

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Late symptoms days to weeks

• Persistent low grade headache
• Light-headedness
• Sleep disturbance
• Easy fatigability
• Intolerance of bright lights or difficulty
  focusing vision
• Intolerance of loud noises, tinnitus
• Irritability and low frustration tolerance
• Anxiety and/or depressed mood
• Poor attention and concentration
• Memory dysfunction

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Second Impact Syndrome

• case series of head and neck trauma in football
  players.
• Death after minor second impacts in players with
  previous concussion syndrome who return
  prematurely to competition
• Schneider 1973
• 17 cases of SIS from 1991-1998 or 1-2 cases/year
• Cantu 1998

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Second impact syndrome

• Pathophysiology (from animal models)
• loss of autoregulation of the brains blood
  supply
• cerebrovascular congestion
• malignant brain swelling and marked increase in
  intracranial pressure
• herniation
• described only in adolescents and adults

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Postconcussive Syndrome

• Fatigue
• Headaches
• Disequilibrium or difficulty in concentrating
  that may persist for weeks to months after the
  initial injury

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Cumulative neuropsychological impairment

• 20 adults (16-26 yo) after a 2nd concussion vs
  matched controls (1st concussion)
• decrease in rate of information processing
• longer recover time
• deficits with increasing severity and duration of
  mental status abnormalities subsequent to each
  separate concussion
• Gronwall, Lancet 1975

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Cumulative neuropsychological impairment

• Brain damage in boxers. punch-drunk syndrome,
  dementia pugilistica
• Head blows throughout a career may result in
  early degenerative neurological conditions and
  gross cognitive impairment
• Muhammad Alis form of Parkinsons
• AAN ban on boxing

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• When is it appropriate for an athlete who has a
  concussion to return to play?

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Guidelines

• management of concussion remains a matter of
  controversy due to absence of evidence-based data
  
• plethora of guidelines (gt 20)
• based on clinical judgment and experience
• variable emphases on assessment of confusion,
  LOC, and/or post traumatic amnesia

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Guidelines

• 3 main management issues
• the appropriate management of the acutely injured
  athlete to identify potential neurosurgical
  emergencies
• the prevention of catastrophic outcome related to
  acute brain swelling
• the avoidance of cumulative brain injury related
  to repeated concussions

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Quigleys rule 1945

• Athletes should discontinue participation in
  sports after 3 cerebral concussions

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Cantu 1986

• Widely used and adopted by the American College
  of Sports Medicine (ACSM)

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Colorado Medical Society 1991

• formulated in response to several deaths
  secondary to head injuries in Colorado high
  school football players

21
American Academy of Neurology 1997

• Consensus group of neurologist, neurosx, sports
  med, athletic trainers, players, etc

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Concussion in sport group (CISG)

• Vienna 2001, Prague 2004
• International symposium on concussion in sport,
  organized by the IIHF, FIFA, IOC
• Revised consensus definition a complex
  pathophysiologic process affecting the brain,
  induced by traumatic biomechanical forces.
• Emphasized the detailed concussion history
• specific ?s as to previous concussive symptoms
  rather than perceived number of past concussions

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CISG

• Recommendations
• Injury grading scales be abandoned in favor of
  combined measures of recovery
• Individualized return-to play guide
• Concussion severity retrospectively determined
  after
• all concussion symptoms have cleared,
• the neuro exam is normal,
• cognitive function has returned to baseline.

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CISG

• New classification of concussion in sport
• Simple concussion
• Injury resolves without complication over 7-10
  days
• Cornerstone of management is rest until all
  symptoms resolve and then graded program of
  exertion before return to sport
• Complex concussion
• Persistent sx (including sx recurrence with
  exertion)
• Specific sequelae (seizures, prolonged LOC gt
  1min, prolonged cognitive impairment)
• H/O multiple concussions or repeated concussions
  with progressively less impact force
• Formal neuropsychological testing plus other
  investigations

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Concussion Management Acute injury

• ANY signs or symptoms of a concussion
• Should not be allowed to return to play in the
  current game or practice
• Should not be left alone regular monitoring for
  deterioration
• Should be medically evaluated
• Return to play must follow a medically supervised
  stepwise process
• When in doubt, sit them out!

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Sideline evaluation
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Sport Concussion Assessment Tool

• SCAT developed by combining existing tools into
  a new standardized tool for
• Patient education
• Physician assessment of sports concussion

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SCAT
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SCAT
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Return to play protocol

• physical and cognitive rest
• Step-wise process
• 1. No activity, complete rest. Once
  asymptomatic, proceed to step 2
• Light aerobic exercise (walking, stationary
  cycling, no resistance training)
• Sport specific exercises progressive addition of
  resistance training at steps 3 4
• Non-contact training drills
• Full contact training after medical clearance
• Game play
• if any sxs, drop back to previous asymptomatic
  level and try to progress in 24 hrs

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Neuropsychological testing

• Assessment of cognitive function
• Should not be the sole basis of a return to play
  decision but rather as an aid to the clinical
  decision making
• Should not be done while the athlete is
  symptomatic since it adds nothing to
  return-to-play decisions
• benefit of baseline pre-injury testing and serial
  post-injury follow-up

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Neuroimaging

• Conventional modalities usually normal
• Head CT (or MRI) contributes little to concussion
  evaluation except whenever suspicion of an
  intra-cerebral structural lesion exists
• Prolonged disturbance of conscious state
• Focal neurologic deficit
• Worsening symptoms
• Newer structural MRI modalities (gradient echo,
  perfusion, and diffusion weighted) have greater
  sensitivity for structural abnormalities but
  limited use currently

33
Conclusions

• Repetitive concussions increase the risk of
  second impact syndrome and post-concussive
  syndromes
• NO athlete should return to sport until all
  concussive symptoms have resolved at rest and
  with exertion
• Goal to prevent catastrophic outcomes of acute
  structural brain injury, second impact syndrome,
  and cumulative brain injury due to repetitive
  trauma.
• All athletes suspected of having sustained
  concussions should undergo thorough evaluation,
  including neurologic screening exam,
  neuropsychological testing, and exertional
  provocative maneuvers.

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Back to the case

• Concussive severity grade 3 or complex
  concussion
• Discharge instructions should include
• No activity, complete rest until seen by PMD in
  1-2 days
• May return-to-play only when asymptomatic gt 1-2
  weeks and only with medical clearance

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Questions?
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Bibliography

• American Academy of Neurology. Practice
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• Aubry M. Summary and agreement statement of the
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• Cantu R. Second-impact syndrome. Clinical Sports
  Med 1998137-44
• Evans R. Concussion and mild traumatic brain
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• Gronwall D. Cumulative Effect of Concussion.
  Lancet 19752995-7
• Harmon K. Assessment and Management of
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