Biopsychology of Stress PSY4920

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Biopsychology of Stress PSY4920

• Elaine M. Hull
• TTh 930-1045
• Eppes Rm. 214

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Contact Information

• Office Eppes 318
• E-mail hull_at_psy.fsu.edu
• Phone [phone]
• Office hours MWF 1000 - 1100 and by
  appointment

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Text Why Zebras Dont Get Ulcers

• Robert Sapolsky (3rd Edition)
• Supplementary material posted on my Psychology
  Department Web site
• http//www.psy.fsu.edu/

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Format

• Lectures
• Group presentations
• Lots of discussion

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Grading

• 2 multiple choice exams, 30 points each
• 2 oral exams, 10 points each
• 1 paper or oral presentation, 20 points
• OPTIONAL 2-part final to take the place of 1 or
  both of the multiple choice exams.
• Final grade will be the sum of all of the above

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Oral exams

• 1 week before each oral exam you will receive a
  list of 50 questions.
• On exam day students will be chosen in random
  order to answer 1 question.
• If correct ? 10 points
• If incorrect ? second question worth up to 5 pts
• Students may volunteer to answer missed questions
  for a , 3 of which will add 1 pt to his/her
  grade

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Oral exams

• I will offer hints, if you are close to the right
  answer, but not quite fully correct.
• If you suffer from panic disorder and wish to
  answer your question BEFORE the classs oral
  exam, I will randomly choose one question to ask
  in my office.

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Group presentations

• Must be accompanied by a 1-2 page outline of main
  points references.
• Submit to me at least 1 day before your
  presentation, so I can post it for the class.
• Also, please submit any PowerPoint file, so I can
  post that for the class, instead of the outline.
  (I also want the outline and refs.)

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Oral presentations

• You can choose any topic covered by Sapolsky or
  listed in the syllabus, but please check with me
  in advance.
• Possible types of presentation
• Debate
• Quiz or talk show
• Skit
• Lecture

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Papers

• You can choose any topic covered by Sapolsky or
  listed in the syllabus, but please check with me
  in advance.
• Must be in electronic form and hard copy.
• Must be accompanied by a 1-2 page outline of main
  points references.
• It will be due the same day as that topic is
  covered in class.

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Schedule of Topics

• 8/28 Ch. 1. Why dont zebras get ulcers?
• 8/30 Ch. 2. Glands, gooseflesh, hormones
• 9/1 The Cardiovascular System, begin Ch. 3
• 9/4 Ch.3. Strokes, heart attacks voodoo death
• 9/6 Ch. 4. Stress, metabolism, liquidating
  assets
• 9/8 Ch. 4, continued
• 9/11 Ch. 5. Ulcers, colitis the runs
• 9/13 REVIEW
• 9/15 ORAL EXAM

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Schedule of Topics

• 9/18 Ch. 8. Immunity, stress and disease
• 9/20 Ch. 8, cont.
• 9/22 Ch. 9. Stress and pain
• 9/25 Ch. 12 . Aging and death
• 9/27 Ch. 13. Why is psychological stress
  stressful?
• 9/29 Ch. 17. The view from the bottom
• 10/2 Ch. 17, cont.
• 10/4 Ch. 18. Managing stress
• 10/6 Ch. 18, cont.
• 10/9 REVIEW
• 10/11 WRITTEN EXAM

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Schedule of Topics

• 10/13 GROUP PRESENT Importance of mothering
• 10/16 NO CLASS, Prepare presentation/paper
• 10/18 NO CLASS, Prepare presentation/paper
• 10/20 Ch. 6. Importance of active mothering
• 10/23 Ch. 7. Stress reproduction
• 10/25 GROUP PRESENTATION, Ch. 7, cont.
• 10/27 GROUP PRESENTATION, Stress memory
• 10/30 Ch. 10. Stress memory
• 11/1 Ch. 11. Stress a good nights sleep
• 11/3 Ch. 11, cont.
• 11/6 REVIEW
• 11/8 ORAL EXAM

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Schedule of Topics

• 11/10 NO CLASS Veterans Day
• 11/13 GROUP PRESENT Stress, depressn, Ch 14
• 11/15 GROUP PRESENT Eating disorders, Ch. 14
• 11/17 GROUP PRESENT Exercise R. to stress
• 11/20 GROUP PRESENT Personality Stress
• 11/22 Ch. 15. Personality, temperament, stress
• 11/24 NO CLASS THANKSGIVING
• 11/27 Ch. 15, Cont.
• 11/29 GROUP PRESENT Stress Drug addiction
• 12/1 Ch. 16. Junkies, adrenaline junkies,
  pleasure
• 12/4 Ch. 16, cont.
• 12/6 REVIEW
• 12/8 WRITTEN EXAM

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What is stress?
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Acute physical stressorsLions
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Chronic physical stressorsDrought , famine
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Chronic physical stressorsparasites
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Psychological, social stressorsTraffic.
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Psychological, social stressors Relationships,
care for dying relative
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Psychological, social stressorsDebt
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What is a stressor?

• Anything that throws body out of allostatic
  balance
• Homeostasis maintenance of single optimal level
• Allostasis range of measures appropriate for
  situation (sleep vs. bungee-jumping)
• Heat, cold, illness, injury, hunger
• Includes anticipation of event, empathy

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What is the stress response?

• The bodys attempt to restore balance.
• Its great for dealing with acute physical
  stressors, but can be disastrous if activated all
  the time.

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Hans Selye

• Early research project Ovarian extractWhat
  does it do?
• Inject rats every day ? ulcers, enlarged adrenal
  glands, shrunken immune tissues
• So did control rats!!
• So did others subjected to cold, heat, forced
  exercise, surgical procedures
• Stress!

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Selye General Adaptation Syndrome

• ALARM
• initial response (sympathetic NS)
• Mobilize energy from stores, inhibit further
  storage
• Tornado no time to repaint the kitchen
• Inhibit digestion, growth, reproduction, immunity
• Increase HR, BP, breathing
• Walter Cannon Fight or flight response
• Analgesia
• Aspects of senses and memory improve

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Selye General Adaptation Syndrome

• RESISTANCE, if stressor continues
• Cortisol increases blood glucose ( heating house
  by burning furniture)
• Liver
• Gluconeogenesis Amino acids, glycerol ? glucose
• Glycogenolysis Glycogen ? glucose
• Skeletal muscle
• Decrease protein synthesis, increase degradation
• Decrease glucose uptake
• Fat
• Decrease glucose uptake increase lipid
  mobilization

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Selye General Adaptation Syndrome

• RESISTANCE (cont.)
• Cortisol
• Anti-inflammatory
• Decrease vasodilation, capillary permeability
• Immunosuppression
• Decrease antibody production
• Decrease circulating lymphocytes

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Selye General Adaptation Syndrome

• EXHAUSTION
• Resources depleted (penny-wise, dollar-foolish)
• Never store extra energy fatigue rapidly
  increase chance of diabetes
• Increased blood pressure, heart disease, strokes
• Reproductive disorders
• Hippocampus neurons destroyed
• Immune suppression

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There is hope!

• Individual differences in physiological responses
• Individual differences in coping strategies