A Modern Approach to Controlling ICP Spray Chamber Temperature

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A Modern Approach to Controlling ICP Spray
Chamber Temperature

• Jerry Dulude, Glass Expansion, jdulude_at_geicp.com

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Limitations of Externally Controlled Spray
Chambers

• Requires antifreeze solution
• Requires bulky floor model chiller
• Cumbersome coolant lines from chiller to chamber
• Freezing of condensate on lines
• Requires intricate jacketed chamber

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Limitations of other Peltier Controlled Spray
Chambers

• Lack of programmability
• Insufficient cooling
• Require external fluid supply
• Limited temperature range
• Limited compatibility

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IsoMist Programmable Temperature Spray Chamber
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Features of IsoMist

• Powerful Peltier-effect chiller reaches -5C in 15
  minutes
• Programmable from -10 to 60C in 1 degree
  increments
• Maintains temperature to within 0.1 degree
• Compact design (7.5x4x4 inches)
• 100 self-contained (no external lines)
• Incorporates Bluetooth technology for clean
  wireless control (USB available)

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PC Screen showing IsoMist Software
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Variety of Cyclonic Spray Chambers

• Borosilicate glass most aqueous and organic
  applications
• Quartz Trace boron determinations
• PFA HF and ultra trace applications

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Applications of the IsoMist

• Analyze volatile solvents Low temp.
• Reduce oxide interferences Low temp.
• Lower detection limits High temp.
• Increase stability Constant temp.

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Determination of Trace Metals in Naphtha

• Interfere with the cracking process
• Poisoning of the catalysts
• Environmental release concerns
• Origin and migration markers

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Spike Recoveries in Light NaphthaDirect (no
dilution)
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Oxide Reduction in ICP-MSIsobaric oxide
interferences
Element/Isotope Interference
56Fe 40Ar16O
51V 35Cl16O
44Ca 14N14N16O
48Ti 32S16O
52Cr 34S18O
64Zn 32S16O16O
64Zn 48Ca16O
Robert Thomas, Practical Guide to ICP-MS, Marcel
Dekker, NY, 2004.
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Reducing Oxides for ICP-MS
Data courtesy of David Jones, ALS Chemex,
Brisbane, Australia
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Analysis of Limited Sample Volumes

• Biological applications
• Intracellular fluids
• Neonatal samples
• Forensic applications
• Requires micro flow nebulization
• Low DLs desirable

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Effect of Temperature on Normalized LOD (20ul/min
Uptake)
PE Optima 2100DV
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Constant temperature benefits

• Environmental monitoring
• Tighter CCVs
• Fewer QCs
• Higher productivity
• Metal assays
• Tighter bracketing
• Higher accuracy

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IsoMist Customization
Models

• PE ICP ICP-MS
• Varian ICP ICP-MS
• Agilent ICP-MS
• ThermoFisher ICP ICP-MS
• Horiba J-Y ICP
• Teledyne Leeman ICP
• GBC ICP
• Spectro ICP

Spray Chamber Materials

• Borosilicate glass
• Quartz
• Inert PFA

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Chassis Configurations of IsoMist
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IsoMist on Optima 2100DV
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IsoMist on Optima 2100DV
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IsoMist on the Agilent 7500 ICP-MS
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IsoMist on the Varian Vista MPX
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IsoMist on the Varian Vista MPX
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IsoMist on the Thermo iCAP 6500DV
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IsoMist on the PE Elan 9000
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IsoMist on the PE Elan 9000
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Summary

• Control of Spray chamber temperature enhances the
  capability of your ICP.
• The IsoMist is easily installed.
• The IsoMist is easily and precisely controlled.
• Compatible with all major ICP-OES ICP-MS models.