NIDA Research Training Directors

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NIDA Research Training Directors Meeting
Division of Clinical Neuroscience and Behavioral
Research (DCNBR) Joseph Frascella,
Ph.D. Bethesda, Maryland November 3, 2006
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Division of Clinical Neuroscience and Behavioral
Research (DCNBR)
Provide a translational approach within a
clinical research context to advance our
understanding of Brain, Behavior Health in
Drug Abuse and Addiction
through
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Division of Clinical Neuroscience and Behavioral
Research (DCNBR)
Clinical Neuroscience Brain
Behavioral Development Behavioral
Integrative Treatment
Major Programs
BEHAVIOR
BRAIN
HEALTH
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Clinical Neuroscience Branch
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Clinical Neuroscience Branch
Major Goals

• To advance our understanding of the
• clinical neurobiology of drug abuse and
  addiction
• To advance our understanding of the biological
  etiology of drug addiction

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Clinical Neuroscience Branch

• Research Programs
• Neurobiology of Addiction
• Translational Research
• Cognitive Neuroscience
• Biological Etiology/Human Genetics/Individual
  Differences
• Comorbidity
• Neurobiology of HIV/AIDS Neurobiology of
  Risky Behavior
• Neurobiology of Human Pain and Analgesia

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Behavioral and Brain Development Branch
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Behavioral and Brain Development Branch
Major Goals

• Increase understanding of how developmental
  processes and outcomes in humans are affected by
  drug use/exposure and related factors (e.g.,
  environment)
• Increase understanding of behavioral and brain
  processes in human development as directly
  related to drug use, drug abuse, and associated
  risk behaviors
• Support research on understanding brain and
  behavioral processes in normal development that
  may be influenced by drug exposure
• Support research on interventions designed to
  minimize negative consequences of drug
  use/exposure and related factors on human
  development

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Behavioral and Brain Development Branch
Research Programs

• Prenatal Drug Exposure Developmental Outcomes
• Postnatal Effects of Drug Use/Abuse
  Behavioral/Brain Development
• Interventions Ameliorate Negative
  Consequences of Drug Exposure/Environment, Use,
  and Abuse
• Pediatric Neuroimaging Application in
  Brain/Behavioral Development
• Developmental Processes Underlying Risk
  Behaviors (e.g., HIV risk
• behaviors)
• Drug Use Consequences among Youth w/ Mental
  Health Conditions

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Behavioral IntegrativeTreatment Branch
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Behavioral Integrative Treatment Branch
Major Goals

• To produce effective and ultimately community
  friendly behavioral treatments (including
  integrative behavioral and pharmacological
  treatments and complementary/ alternative
  treatments) for drug abuse and addiction
• To determine the best ways to promote adherence
  to drug abuse treatments, including adherence to
  treatments for comorbid disorders (e.g.,
  HIV/AIDS, depression, etc.) in drug abusing
  populations 

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Behavioral Integrative Treatment Branch

• Research Programs
• Behavioral Therapies Development
• Combined Behavioral with Pharmacotherapies
• AIDS Risk Reduction
• Comorbidity Mental and Drug Abuse Disorders
• Drug Abuse Treatment in Primary Care Settings
• Special Populations

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Division of Clinical Neuroscience and Behavioral
Research (DCNBR)
Opportunities for Advancement of the Science

• translational research
• new approaches to behavioral treatment
• emphasis on gene-environment-development
  interaction
• brain imaging of genetic variations behavioral
  treatment
• comorbidity
• assess early environmental influences (e.g.,
  drugs stress
• drugs violence drugs deprivation) on
  development
• neurobiology
• sleep disturbance and drug abuse/addiction

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Division of Clinical Neuroscience and Behavioral
Research (DCNBR)
Attracting New Investigators -- New PIs PIs
New to NIDA

• I/START (Imaging/Science Track Award for
  Research Transition)
• Program
• Using R21s and R03s as beginner grants
• RFAs
• R21 only
• mixed R21/R01 with different review criteria
• Organizing meetings in new program areas
• Encouraging junior investigators to attend
  workshops
• Grant-writing workshops
• Minority Supplements
• Training infrastructure (T32s, centers, Ks)