CHARACTERISTICS

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See also In Focus Nimesulide Gel by Adis
International
A new multifactorial opportunity for the
symptomatic treatment of pain associated with
sprains and acute traumatic tendinitis. Character
isticsThe topical route of administration
confirm the multifactorial mode of action of
nimesulide. Nimesulide gel reduces oedema,
inflammation and pain thanks to its inhibitory
effect on the release of inflammatory mediators
(i.e. histamine, PAF, arachidonic acid
metabolites and A4-leukotriene)
Characteristics of nimesulide gel and related
advantages

• CHARACTERISTICS
• Aqueous, alcohol-free gel
• formulation
• Formulation contains Transcutol,
• a vehicle enhancing transcutaneous
• penetration
• No absorption of active ingredient
• (pharmacologically inactive at
• systemic level)
• Efficacy equal to diclofenac
• and higher than placebo

• ADVANTAGES
• Less local irritation, also confirmed by
• a clinical study in healthy volunteers
• High efficacy guaranteed at the site
• affected by inflammation
• No risk of systemic side effects
• Strong anti-inflammatory and analgesic
• efficacy