Academic Outreach & Non-Profit Screening Market Trends 2014

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Academic Outreach Non-Profit Screening Trends
2014byHtStec

• This Report will be available from 1st Feb 2014.
• Explore all reports for Healthcare Services
  market _at_
• http//www.rnrmarketresearch.com/reports/life-scie
  nces/healthcare/services

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Academic Outreach Non-Profit Screening Trends
2014

•   This market report summarizes the results of
  HTStecs 2nd global web-based benchmarking survey
  on academic outreach and non-profit screening
  centers carried out in January 2014.
•   The study was initiated by HTStec as part of
  its ongoing tracking of emerging life science
  marketplaces. The current document updates and
  extends HTStecs previous (June 2011) report on
  this subject.
•   The main objectives of this global
  benchmarking study were to compile a report that
  comprehensively documents the current status,
  operational capabilities, interests, assay
  readouts, formats, funding, budgets, success
  criteria and future investments of academic and
  non-profit screening centers.
•   The report is intended as a reference/resource
  document that will facilitate identifying
  screening centers with certain capabilities or
  interests, and the direct comparison
  (benchmarking) of the screening centers surveyed.
  It is anticipated that the report will be of
  interest to 3rd parties seeking comparative data
  and a concise summary of information on academic
  outreach and non-profit screening
• Complete report available _at_ http//www.rnrmarketre
  search.com/academic-outreach-non-profit-screening-
  trends-2014-market-report.html

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Academic Outreach Non-Profit Screening Trends
2014

• The survey looked at the following aspects of
  academic outreach and non-profit screening as
  practiced today (2014) by the screening centers
  surveyed full name of the screening center, the
  organisation/institution to which the screening
  center is affiliated and its geographic location
  type of organisation/institution the screening
  center is affiliated with the centers focus
  activities undertaken at the center aspects of
  the screening process the center supports
  details of the compound libraries used or
  available to the center application areas or
  disease focus of the center focus on certain
  therapeutic targets target classes the center is
  most experienced in screening screening
  capabilities in 2013 in terms of the number of
  therapeutic targets screened per year and the
  total number of wells (all targets) screened per
  year maximum throughput for certain assay types
  typical duration of a screening project of
  screens undertaken that were cell-based,
  biochemical or whole organism microplate formats
  used for the majority of assays undertaken most
  used final assay volume and maximum DMSO
• Complete report available _at_ http//www.rnrmarketre
  search.com/academic-outreach-non-profit-screening-
  trends-2014-market-report.html

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Academic Outreach Non-Profit Screening Trends
2014

• The main questionnaire consisted of 38
  multi-choice questions and 3 open-ended
  questions.
•   All of the persons that completed the survey
  held a senior job role or position at their
  screening center, which was in descending order
  23 directors 11 managers 9 heads and 8 with
  other senior job roles.
•   All survey results were expressed as an
  average of all screening centers on the summary
  pages. In addition, all the individual responses
  from each screening center to every question are
  presented in the detail pages.
•   55 screening centers participated in the
  survey. Of these 93 (51 out of 55) provided
  comprehensive input.
•   Screening centers were geographically split
  60 North America 34 Europe 4 Rest of World
  and 2 Asia (excluding Japan). The majority (56)
  of screening centers surveyed came from the USA.
• Complete report available _at_ http//www.rnrmarketre
  search.com/academic-outreach-non-profit-screening-
  trends-2014-market-report.html

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Academic Outreach Non-Profit Screening Trends
2014

• The majority of screening centers were
  affiliated to a university/academic core
  facility.
•   The screening focus of the majority of centers
  surveyed was a combination of both drug and probe
  discovery depending on need or funding.
•   The main activity undertaken by the screening
  centers was internal drug discovery or probe
  screening with data confidential to
  organization/institute.
•   The aspects of the screening process most
  supported by screening centers were assay
  development and low to medium throughput
  screening.
•   The compound libraries that screening centers
  most use were third party libraries (e.g.
  commercial vendor libraries).
•   Screening centers compound libraries were made
  up primarily of small molecules.
•   The approximate current size of the library
  held by screening centers was a median of
  100-300K compounds.
• Complete report available _at_ http//www.rnrmarketre
  search.com/academic-outreach-non-profit-screening-
  trends-2014-market-report.html

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Academic Outreach Non-Profit Screening Trends
2014

• The typical size of the screening set used by
  screening centers was a median of 50-100K
  compounds per screen.
•   The majority of screening centers had no main
  application area or disease focus. The
  application area/disease most investigated by
  screening centers was cancer/oncology.
•   Only 6 of screening centers specialize and
  focus on a specific therapeutic target.
•   The target classes that screening centers have
  had most experience of screening over the past 3
  years were kinases, phenotypic (cell-based
  target-agnostic) and protein-protein
  interactions.
•   The number of therapeutic targets screened per
  year by screening centers in 2013 was a median of
  6-10 targets.
•   The total number of wells screened per year by
  screening centers in 2013 was a median of 100K-1M
  wells.
• Complete report available _at_ http//www.rnrmarketre
  search.com/academic-outreach-non-profit-screening-
  trends-2014-market-report.html .

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Academic Outreach Non-Profit Screening Trends
2014

• Screening centers maximum throughput
  capabilities (median number of wells processed
  per week) were as follows 50K-100K wells/week
  for enzyme/biochemical assays 5-50K wells/week
  for cell-based assays, HCS assays, label-free
  assays and phenotypic screens and lt5K wells/week
  for mass spec/NMR assays.
•   The typical duration of a screening project
  undertaken by screening centers (i.e. including
  any assay development, confirmation of hit or
  probe activity, and follow-up assays) was a
  median of 7-9 months.
• The makeup of screen types run at screening
  centers today was 59 cell-based, 35 biochemical
  and 6 whole organism.
•   The microplate format most used in screening
  centers operations was 384-well (standard
  volume).
•   The median final assay volume most used in
  screening center operations was in the range
  25µL-50µL.
• Complete report available _at_ http//www.rnrmarketre
  search.com/academic-outreach-non-profit-screening-
  trends-2014-market-report.html

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Academic Outreach Non-Profit Screening Trends
2014

• For more details contact Mr. Priyank Tiwari
  sales_at_rnrmarketresearch.com / 18883915441

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