Title: eczema Diseases Treatement in singapore
1Herose Pharma
2Eczema / Atopic Dermatitis
- Atopic dermatitis (AD) is a chronic itchy
inflammatory skin disorder that affects about 10
of children to some extent. Many children with AD
develop other symptoms of atopy such as food
allergies, asthma, and allergic rhinitis
(hayfever). When inhaled or ingested allergens
enter the bloodstream they can be carried to the
skin, where they induce a chronic inflammation --
know as atopic dermatitis in sensitized
(atopic) individuals who possess T cells and IgE
specific for an allergen. Allergens that act by
direct skin contact can also incite inflammation.
The immunologic response of the skin to antigen
is complex, resulting in inflammation and
localized tissue destruction. This chronic
inflammation is called eczema and is the most
prominent symptom of atopic dermatitis. - DiagnosisHistory in infancy, clinical findings
(typical distribution sites, morphology of
lesions, while dermatographism).
3Physical Examination
4Physical Examination
Acute Poorly defined erythematous patches,
papules, and plaques with or without scale. Edema
with widespread involvement skin appears puffy
and edematous. Erosions moist, crusted. Linear
or punctuate, resulting from scratching.
Secondarily infected sites S. aurous. Oozing
erosions and/or pustules (usually
follicular). Chronic Lichenification
(thickening of the skin with accentuation of skin
markings) results from repeated rubbing or
scratching. Fissures painful, especially in
flexures, on palms, fingers, and soles. Alopecia
lateral one-third of the eyebrows as a result of
rubbing. Characteristic infraorbital fold in the
eyelids (Dannie-Morgan sign).
5 Eczema / Atopic Dermatitis