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Diabetes journal

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International Journal of Diabetology & Vascular Disease Research (IJDVR) ISSN:2328-353X is an Open Access and a comprehensive journal devoted to Diabetes & Vascular Disease Research. IJDVR, published by SciDoc, includes high quality papers, which cover all major areas of Diabetes, Vascular Diseases and its diagnosis. – PowerPoint PPT presentation

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Title: Diabetes journal


1
International Journal of Diabetology
Vascular Disease Research IJDVR
http//scidoc.org/IJDVR.php
ISSN-2328-353X
2
  • Article name
  • Harmonizing Eating and Exercise Circadian
    Rhythms for Optimal Glucose-Insulin and Vascular
    Physiology
  • This article establishes a global but individual
    public program based on rhythmic circadian eating
    and exercise extent and rate to harmonize
    intermediary metabolism. This will help optimize
    glucose assimilation and insulin dynamics towards
    healthier heart and vascular functions. Any and
    every circadian meal must have its matching
    physical activity to optimize substrate oxidation
    and waste management.
  • Link http//scidoc.org/IJDVR-2328-353X-03-301.ph
    p
  • Article Name
  • An Increase of Maximal Intima-Media
    Thickness in Bilateral Carotid Arteries Strongly
    Suggests the Existence of Coronary Stenosis in
    Japanese Type 2 Diabetic Patients
  • An association of an increase of
    maximal intima-media thickness (IMT) of carotid
    artery to coronary artery stenosis was evaluated
    in Japanese type 2 diabetic (T2DM) out-patients
    without any typical cardiac symptoms or history.
    Maximal IMT from common carotid artery to
    internal carotid artery was measured by
    ultrasonography in T2DM outpatients without any
    typical symptoms or history of coronary artery
    disease (CAD). The patients with a significant
    increase of maximal IMT over 1.5 mm were
    consulted to cardiologists, and the existence of
    coronary artery stenosis was evaluated by
    multiple detector-row computed tomography (MDCT).
    The patients with coronary artery stenosis
    suspected by MDCT were additionally evaluated the
    existence of CAD by coronary angiography. From
    April 2013 to December 2014, we found 17 patients
    with an increase of maximal IMT in bilateral
    carotid arteries and 9 patients with an increase
    of maximal IMT in unilateral carotid artery in
    T2DM outpatients. The patients with a significant
    increase of maximal IMT in bilateral carotid
    arteries had higher incidence of coronary artery
    stenosis by coronary angiography (76.5 )
    thanthose in unilateral carotid artery (11.1).
    The 47.1 of the patients with an increase of
    maximal IMT in bilateral carotid arterieswas
    judged to needpercutaneous coronary intervention
    therapy. In conclusion, a significant increase of
    maximal IMT in bilateral carotid artery strongly
    suggests the existence of coronary artery
    stenosis in Japanese T2DM patients. Screening of
    maximal IMT in bilateral carotid arteries should
    be beneficial for the detection of silentischemia
    in coronary artery.
  • Link http//scidoc.org/IJDVR-2328-353X-03-201.ph
    p

3
  • Article Name
  • Pathophysiologic Aspects of Hypertension
  • Hypertension is defined as a sustained
    increase in blood pressure. Historically, the
    level of blood pressure designating hypertension
    has been a systolic blood pressure of 140 mm Hg
    or more and/or a diastolic blood pressure of 90
    mm Hg or more. However, the risk imparted with
    increasing blood pressure is continuous, such
    that the level of blood pressure must be
    considered within the context of the overall
    cardiovascular risk profile. Clearly,
    antihypertensive treatment helps to prevent both
    cardiovascular and cerebrovascular events, the
    dreaded complications of increased blood
    pressure. Nevertheless, hypertension remains
    unrecognized or inadequately treated in the great
    majority of patients. This work aims to review
    the essential key element for the understanding
    of hypertension's pathophysiology.
  • Link http//scidoc.org/IJDVR-2328-353X-03-101.ph
    p
  • Article Name
  • Effect of Aqueous Extract from Erythrea
    Centaurium in Merione Shawi
  • The aqueous extract of E. centaurium,
    administered to merione at 200 mg/kg for 6 months
    produced a significant reduction in glycemia,
    insulinemia, fructosamine and glycosylated
    haemoglobin. It also exhibited an important
    decrease of lipidic parameters such as
    cholesterol, LDL-cholesterol, triglycerids. The
    results showed no significant diminution of the
    weight.
  • Link http//scidoc.org/IJDVR-2328-353X-02-701.ph
    p
  • Article Name
  • A Short Review of Some Medicinal Plants
    And Phytocompounds With Hypotensive And
    Hypoglycemic Activities
  • This paper aims to review some medicinal
    plants and compounds of botanical origin which
    are capable to lower plasma glucose levels and
    blood pressure. Hypoglycemic natural products
    comprise flavonoids, xanthones, triterpenoids,
    alkaloids, glycosides, alkyldisulfides.
    aminobutyric acid derivatives, guanidine,
    polysaccharides and peptides. Hypotensive
    compounds include flavonoids, diterpenes,
    alkaloids, glycosides, polysaccharides and
    proteins.
  • Link http//scidoc.org/IJDVR-2328-353X-02-501.ph
    p

4
  • Article Name
  • On Research to Optimize Eating Timing
    Simple Solutions for Complex Problems
  • Recent accomplishments in animal and
    human physiology have contributed to urgency for
    creating innovative research on timing of
    nutrient intake . These findings suggest that
    feeding and eating times during the 24-h period
    matter in how efficiently nutrients are utilized
    and partitioned into different tissues notable
    splanchnic and peripheral tissues. Shifting
    eating time from morning to evening in once-daily
    fed dairy and beef cattle has increased nutrient
    efficiency and milk fat and energy production.
    Such effects have mainly been resulted from
    altered circadian and postprandial rhythms of
    nutrient intake and energy-yielding metabolites
    and hormones .On the other hand, evidence exists
    that human glucose intolerance and insulin
    resistance develop as day ends and night begins.
    Thus, despite the discovery that evening feeding
    may improve production and economics in
    food-producing animals, due to inter-species
    differences in evolutionary intermediary
    metabolism and eating behaviour, it could
    seriously impair the human physiology and health.
  • Link http//scidoc.org/IJDVR-2328-353X-02-004e.p
    hp
  • Article Name
  • Treatment of Hypercholesterolemia in
    Patients with Diabetes Mellitus
  • Numerous studies have shown that
    statins reduce cardiovascular events including
    stroke and mortality in diabetics. The American
    Diabetes Association 2013 guidelines recommend
    that diabetics at high risk for cardiovascular
    events should have their serum low-density
    lipoprotein (LDL) cholesterol reduced to lt70
    mg/dL with statins. Lower-risk diabetics should
    have their serum LDL cholesterol reduced to lt 100
    mg/dL. The 2013 American College of
    Cardiology/American Heart Association lipid
    guidelines recommend giving high-dose statins to
    adult diabetics aged 75 years with
    atherosclerotic vascular disease (ASCVD) unless
    contraindicated with a class I indication and
    moderate-dose or high-dose statins to diabetics
    with ASCVD 75 years with a class IIa indication.
    Diabetics 21 years with a serum LDL cholesterol
    of 190 mg/dL should be treated with high-dose
    statins with a class I indication. For primary
    prevention in diabetics aged 40 to 75 years and
    serum LDL cholesterol between 70 to 189 mg/dL,
    moderate-dose statins should be given with a
    class I indication. For primary prevention in
    diabetics aged 40 to 75 years, a serum LDL
    cholesterol between 70 to 189 mg/dL , and a
    10-year risk of ASCVD of 7.5 calculated from
    the Pooled Heart Equation, high-dose statins
    should be given with a class IIa indication. For
    primary prevention in diabetics aged 21 to 39
    years or older than 75 years and a serum LDL
    cholesterol between 70 to 189 mg/dL,
    moderate-dose statins or high-dose statins should
    be given with a class IIa indication. There is no
    additional ASCVD reduction from adding nonstatin
    therapy to further lower non-high-density
    lipoprotein (HDL) cholesterol once an LDL
    cholesterol goal has been reached. Clinical
    trials have found no lowering of cardiovascular
    events or mortality in diabetics treated with
    statins by addition of nicotinic acid, fibric
    acid derivatives, ezetemibe, or drugs that raise
    serum HDL cholesterol.
  • Link http//scidoc.org/IJDVR-2328-353X-02-301.ph
    p

5
  • Article Name
  • Hyperglycemic Challenge and Distribution
    of Adipose Tissue in Obese Baboons
  • Background Blood glucose levels
    regulate the rate of insulin secretion, which is
    the bodys mechanism for preventing excessive
    elevation in blood glucose. Impaired glucose
    metabolism and insulin resistance have been
    linked to excess body fat composition. Here, we
    quantify abdominal muscle and abdominal adipose
    tissue compartments in a large nonhuman primate,
    the baboon, and investigate their relationship
    with serum glucose response to a hyperglycemic
    challenge.Methods Five female baboons were
    fasted for 16 hours prior to 90 minute body
    imaging experiment that consisted of a 20-min
    baseline, followed by a bolus infusion of glucose
    (500mg/kg). The blood glucose was sampled at
    regular intervals. The total volumes of the
    muscle, visceral and subcutaneous adipose tissue
    were measured.Results and discussion We found
    that adipose tissue composition predicted
    fluctuations in glucose responses to a
    hyperglycemic challenge of a non-human primate.
    Animals with higher visceral adiposity showed
    significantly reduced glucose elimination. The
    glucose responses were positively correlated with
    body weight, visceral and muscle fat (plt0.005).
    Polynomial regression analysis showed that body
    weight, visceral and muscle were significant
    predictors of serum glucose responses
    (plt0.001).Conclusions These results reveal the
    similarity between humans and baboons with
    respect to glucose metabolism and strengthen the
    utility of baboon for biomedical research.
  • Link http//scidoc.org/IJDVR-2328-353X-02-101.php
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