Title: Tuberculin Test
1Tuberculin Test
- Tuberculin test,a stool of Tuberculosis
diagnosis, is one of two major methods to test
Tuberculin and has replaced many kinds of
puncture test such as tine test to a large
extent. The United Kingdom used tine test until
2005 and then changes to us Tuberculin test. In
addition, Tuberculin test also have a place in
Australia, Canada,Hungary, Netherlands, Portugal,
South Africa and the United States. It has been
recommended to hospitals by both American
Thoracic Society and United States Centers for
Disease Control and Prevention
2Tuberculin Test
- Why need do this Tuberculin test?
- There are mainly three reasons. Firstly, the test
can provide BCG vaccination with evidence. When
the result of the test is active, it means that
the patient has been infected with TB and it is
unnecessary to vaccinate BCG. If the result is
negative, the patient needs vaccination.
Moreover, it can offer the immune action more
evidence. After 3 months of BCG vaccination,
generally, it is advised to do the Tuberculin
test to know that whether organism has produced
immune action to the BCG. If it is active, the
BCG vaccination succeed. On the contrary, if
negative, it need another vaccination. Finally,
it can be used in diagnosis and differential
diagnosis. Tuberculin test plays a vital role in
diagnosis and identification of tuberculosis of
kids and the elderly. It is regarded as a widely
used auxiliary examination methods.
3How it works? The action of Tuberculin is
delayed cellular hypersensitivity. This is the
process antigens enter the organism and
sensitize immune T lymphocytes and T lymphocytes
differentiate and produce a lot of new
lymphocytes. When the sensitive organism are
attacked by antigens again, the sensitive
lymphocytes bind with the antigens and lead to
allergic inflammation. The presence is that the
skin around inject site will produce Scleroma and
Blister. If the result of Tuberculin test is
active, it means that the organism has been
infected with Tuberculin or it has got BCG
vaccination. So these patients have some immunity
to Tuberculin. But there are a few people with
weak immunity will be negative in the test or it
will be negative because of technology problems.
If PPD skin test are negative, in most situation,
it means a failing vaccination. In the end, the
immune features of Tuberculosis can be concluded
that immune action coexists contagion and
hypersensitivity. Resource http//www.creativ
e-diagnostics.com/blog/tuberculin-test/