“Junk DNA” Can Encode the Proteins

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Junk DNA Can Encode the Proteins

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• Subverting the traditional theory junk DNA can
  also encode the proteins.
• Recently, it's reported that some scientists in
  Sweden used a new method for protein analysis and
  they found nearly one hundred kinds of novel gene
  regions for human protein-coding. Many of the
  regions are so-called pseudogenes, and they are
  probably associated with cancer. The researchers
  expected that this new approach will promote a
  whole new field of study.

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• All information about human genome is stored in
  the DNA sequence of nucleus, and scientists have
  already drawn out of the map in the early 21th
  century. Gene refers to different portions of a
  predetermined type of DNA that can encode the
  proteins. In the past few decades, researchers
  used DNA analysis to define approximately 21,000
  human protein-coding genes. In different cell
  types, different protein-coding genes might be in
  the activation or deactivation state, which means
  many medical diseases are related to changes in
  gene activity and specificity.
• In terms of human genome, only about 1.5 percent
  of DNA is composed of protein-coding genes. While
  as for the remain DNA, some regulatory sequences
  are used for adjusting genes protein production.
  But most of the DNA are considered to be a lack
  of use, generally referred to as junk DNA.
  There is a so-called pseudogene in the junk
  DNA, which is always considered as a
  non-functional gene. Certain group of researchers
  also think such gene has lost its function during
  the evolution process.

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• In this latest study, scientists proposed a new
  protein genomics method, making it possible to
  trace the protein-coding genes in the remain
  98.5 DNA, which until now has been regarded as
  an impossible task. Research suggests that some
  pseudogenes generated proteins, indicating that
  they do have a function. The researchers said
  that they had to test the peptide sequence and
  match the whole genome data with millions of
  possible sites.
• In addition, the scientists also developed a new
  experimental and bioinformatics approach to
  conduct protein-based genetic testing, but when
  everything was ready, the researchers just felt
  like they were participating in a genome
  adventure. Cells from the mice also received
  similar findings. Many of the new proteins
  encoded by pseudogenes can be traced in other
  cancer cells, too. The next task for those
  researchers is to know whether the genes in
  genome garbage dump present an important role
  in cancer or any other diseases.

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• The researchers noted that the study of junk
  DNA does challenge the old theory of fake
  protein-coding genes. The proposed method allows
  to conduct the genomic annotation in organisms
  with complicated protein-based genomes, which
  will contribute to find massive new
  protein-coding genes in any species with a known
  DNA sequence in human organisms.
• About Author
• Creative Peptides is specialized in the process
  development and the manufacturing of bioactive
  peptides. It offers custom peptide synthesis,
  process development, GMP manufacturing as well as
  catalog products. Visit http//www.creative-peptid
  es.com/ to know more.
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